Typical Testing Data/Standard Curve (for reference only)
Human Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) ELISA Kit | IFIT2 elisa kit
Human Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) ELISA Kit
Gene Names
IFIT2; P54; G10P2; IFI54; ISG54; cig42; IFI-54; IFIT-2; GARG-39; IFI-54K; ISG-54K; ISG-54 K
Reactivity
Human
Synonyms
Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2); Human Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) ELISA Kit; IFIT2 elisa kit
Reactivity
Human
Sequence Length
472
Samples
Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
Assay Type
Quantitative Sandwich
Detection Range
5ng/L - 2000ng/L
Sensitivity
2.58ng/L
Intra-Assay
CV<8%
Inter-Assay
CV<10%
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for IFIT2 elisa kit
Intended Uses: This sandwich kit is for the accurate quantitative detection of human Interferon-induced Protein with Tetratricopeptide Repeats 2 (also known as IFIT2) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.
Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human IFIT2 antibody. IFIT2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human IFIT2 Antibody is added and binds to IFIT2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated IFIT2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human IFIT2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human IFIT2 antibody. IFIT2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human IFIT2 Antibody is added and binds to IFIT2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated IFIT2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human IFIT2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,632 Da
NCBI Official Full Name
interferon-induced protein with tetratricopeptide repeats 2
NCBI Official Synonym Full Names
interferon induced protein with tetratricopeptide repeats 2
NCBI Official Symbol
IFIT2
NCBI Official Synonym Symbols
P54; G10P2; IFI54; ISG54; cig42; IFI-54; IFIT-2; GARG-39; IFI-54K; ISG-54K; ISG-54 K
NCBI Protein Information
interferon-induced protein with tetratricopeptide repeats 2
UniProt Protein Name
Interferon-induced protein with tetratricopeptide repeats 2
Protein Family
UniProt Gene Name
IFIT2
UniProt Synonym Gene Names
CIG-42; G10P2; IFI54; ISG54; IFIT-2; IFI-54K; P54
Uniprot Description
IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
Research Articles on IFIT2
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Product Notes
The Human IFIT2 ifit2 (Catalog #AAA167315) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA167315 ELISA Kit recognizes Human IFIT2. It is sometimes possible for the material contained within the vial of "Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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