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Western Blot (WB) (Western Blot analysis of 1)Hela, 2)MCF-7, 3)HT-29, 4)Mouse Lung using LGALS3 Polycloanl Antibody at dilution of 1:1000)

Rabbit Galectin 3 Polyclonal Antibody | anti-Gal-3 antibody

Galectin 3 Polyclonal Antibody

Gene Names
Lgals3; GBP; L-34; gal3; Mac-2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
Galectin 3; Polyclonal Antibody; Galectin 3 Polyclonal Antibody; 35 kDa lectin; Carbohydrate binding protein 35; Carbohydrate-binding protein 35; CBP 35; CBP35; Gal-3; GAL3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin 3 internal gene; included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-31; L-34 galactoside-binding lectin; L31; Laminin-binding protein; Lectin L-29; Lectin; galactose binding; soluble 3; LEG3; LGALS2; LGALS3; MAC 2 antigen; Mac-2; Mac-2 antigen; MAC2; Macrophage galactose-specific lectin; MGC105387; anti-Gal-3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
0.47mg/mL (varies by lot)
Sequence Length
264
Applicable Applications for anti-Gal-3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:1000-1:2000
IHC: 1:100-1:400
Immunogen
Recombinant Mouse Galectin-3 protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20?. Avoid freeze/ thaw cycles.

Western Blot (WB)

(Western Blot analysis of 1)Hela, 2)MCF-7, 3)HT-29, 4)Mouse Lung using LGALS3 Polycloanl Antibody at dilution of 1:1000)

Western Blot (WB) (Western Blot analysis of 1)Hela, 2)MCF-7, 3)HT-29, 4)Mouse Lung using LGALS3 Polycloanl Antibody at dilution of 1:1000)

Western Blot (WB)

(Western Blot analysis of 1)Raw264.7, 2)NIH/3T3 using LGALS3 Polycloanl Antibody at dilution of 1:1000)

Western Blot (WB) (Western Blot analysis of 1)Raw264.7, 2)NIH/3T3 using LGALS3 Polycloanl Antibody at dilution of 1:1000)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse lung using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse lung using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse spleen using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse spleen using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Rat lung using LGALS3 Polycloanl Antibody at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Rat lung using LGALS3 Polycloanl Antibody at dilution of 1:200)
Related Product Information for anti-Gal-3 antibody
Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for ?-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis .
Product Categories/Family for anti-Gal-3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Calculated MW: 27kDa
Observed MW: 27kDa
NCBI Official Full Name
Galectin-3
NCBI Official Synonym Full Names
lectin, galactose binding, soluble 3
NCBI Official Symbol
Lgals3
NCBI Official Synonym Symbols
GBP; L-34; gal3; Mac-2
NCBI Protein Information
galectin-3
UniProt Protein Name
Galectin-3
UniProt Gene Name
Lgals3
UniProt Synonym Gene Names
Gal-3; CBP 35
UniProt Entry Name
LEG3_MOUSE

Uniprot Description

galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Extracellular matrix; Cell surface; Motility/polarity/chemotaxis

Cellular Component: cell surface; cytoplasm; external side of plasma membrane; extracellular matrix; extracellular region; extracellular space; immunological synapse; membrane; mitochondrial inner membrane; nucleus; proteinaceous extracellular matrix; spliceosome

Molecular Function: advanced glycation end-product receptor activity; carbohydrate binding; chemoattractant activity; disaccharide binding; IgE binding; laminin binding; monosaccharide binding; protein binding

Biological Process: cell differentiation; eosinophil chemotaxis; extracellular matrix organization and biogenesis; immune system process; innate immune response; macrophage chemotaxis; maintenance of protein localization; monocyte chemotaxis; mRNA processing; negative regulation of apoptosis; negative regulation of endocytosis; negative regulation of T cell receptor signaling pathway; neutrophil chemotaxis; positive chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of serotonin secretion; regulation of T cell proliferation; RNA splicing; signal transduction; skeletal development

Research Articles on Gal-3

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Product Notes

The Gal-3 lgals3 (Catalog #AAA2563549) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Galectin 3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Galectin 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:1000-1:2000 IHC: 1:100-1:400. Researchers should empirically determine the suitability of the Gal-3 lgals3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galectin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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