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Rabbit anti-Human FUT8 Polyclonal Antibody | anti-FUT8 antibody

FUT8 Conjugated Antibody

Gene Names
FUT1; H; HH; HSC
Reactivity
Human
Applications
Most Applications
Synonyms
FUT8; Polyclonal Antibody; FUT8 Conjugated Antibody; Alpha- (1; 6)-fucosyltransferase; MGC26465; anti-FUT8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total FUT8 protein.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-FUT8 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human fucosyltransferase 8 (alpha (1, 6) fucosyltransferase)
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-FUT8 antibody
This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41
NCBI Official Full Name
galactoside 2-alpha-L-fucosyltransferase 1
NCBI Official Synonym Full Names
fucosyltransferase 1 (H blood group)
NCBI Official Symbol
FUT1
NCBI Official Synonym Symbols
H; HH; HSC
NCBI Protein Information
galactoside 2-alpha-L-fucosyltransferase 1
UniProt Protein Name
Alpha-(1,6)-fucosyltransferase
UniProt Gene Name
FUT8
UniProt Synonym Gene Names
Alpha1-6FucT
UniProt Entry Name
FUT8_HUMAN

NCBI Description

This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Aug 2016]

Uniprot Description

FUT8: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Glycan Metabolism - N-glycan biosynthesis; Glycan Metabolism - keratan sulfate biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.68

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: Golgi membrane; Golgi apparatus; membrane; cytoplasm; integral to membrane

Molecular Function: glycoprotein 6-alpha-L-fucosyltransferase activity; SH3 domain binding

Biological Process: integrin-mediated signaling pathway; cell migration; receptor metabolic process; in utero embryonic development; oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation; respiratory gaseous exchange; post-translational protein modification; GDP-L-fucose metabolic process; cellular protein metabolic process; transforming growth factor beta receptor signaling pathway; protein amino acid glycosylation in Golgi; protein amino acid N-linked glycosylation via asparagine; L-fucose catabolic process; N-glycan processing

Research Articles on FUT8

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Product Notes

The FUT8 fut8 (Catalog #AAA9448018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FUT8 Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FUT8 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the FUT8 fut8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FUT8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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