Rabbit anti-Human, Mouse FN3K Polyclonal Antibody | anti-FN3K antibody

FN3K Rabbit Polyclonal

Cat. Num. AAA769406

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: FN3K; Polyclonal Antibody; FN3K Rabbit Polyclonal; anti-FN3K antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 309

• Applicable Applications for anti-FN3K antibody: ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)
• Immunogen: Fructosamine 3 kinase
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS769406 (FN3K antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 11545906
• NCBI GeneID: 64122
• NCBI Accession #: NP_071441.1
• NCBI GenBank Nucleotide #: NM_022158.3
• Molecular Weight: 35,171 Da
• NCBI Official Full Name: fructosamine-3-kinase
• NCBI Official Synonym Full Names: fructosamine 3 kinase
• NCBI Official Symbol: FN3K
• NCBI Protein Information: fructosamine-3-kinase
• UniProt Protein Name: Fructosamine-3-kinase
• Protein Family: Fructosamine-3-kinase
• UniProt Gene Name: FN3K
• UniProt Entry Name: FN3K_HUMAN

NCBI Description

A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]

Uniprot Description

FN3K: May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme. Belongs to the fructosamine kinase family.

Protein type: EC 2.7.1.-; Kinase, other

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: cytosol

Molecular Function: fructosamine-3-kinase activity; kinase activity

Biological Process: epithelial cell differentiation; fructosamine metabolic process; fructoselysine metabolic process; phosphorylation; post-translational protein modification