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Western Blot (WB) (FKBP6 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the FKBP6 antibody detected the FKBP6 protein (arrow).)

Rabbit anti-Human FKBP6 Polyclonal Antibody | anti-FKBP6 antibody

FKBP6, CT (FKBP6, FKBP36, Peptidyl-prolyl cis-trans isomerase FKBP6, 36kD FK506-binding protein, FK506-binding protein 6, Immunophilin FKBP36, Rotamase) (PE)

Gene Names
FKBP6; FKBP36
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
FKBP6; Polyclonal Antibody; CT (FKBP6; FKBP36; Peptidyl-prolyl cis-trans isomerase FKBP6; 36kD FK506-binding protein; FK506-binding protein 6; Immunophilin FKBP36; Rotamase) (PE); Rotamase; anti-FKBP6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Sequence Length
327
Applicable Applications for anti-FKBP6 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
FKBP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from the C-terminal region of human FKBP6.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(FKBP6 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the FKBP6 antibody detected the FKBP6 protein (arrow).)

Western Blot (WB) (FKBP6 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the FKBP6 antibody detected the FKBP6 protein (arrow).)
Related Product Information for anti-FKBP6 antibody
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male meiosis.
Product Categories/Family for anti-FKBP6 antibody
References
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010). Jarczowski, F., et al. J. Biol. Chem. 284(2):766-773(2009). Jarczowski, F., et al. Biochemistry 47(26):6946-6952(2008). Zhang, W., et al. Reproduction 133(2):511-516(2007). Miyamato, T., et al. Cell. Mol. Biol. Lett. 11(4):557-569(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform a
NCBI Official Synonym Full Names
FKBP prolyl isomerase 6
NCBI Official Symbol
FKBP6
NCBI Official Synonym Symbols
FKBP36
NCBI Protein Information
inactive peptidyl-prolyl cis-trans isomerase FKBP6
UniProt Protein Name
Inactive peptidyl-prolyl cis-trans isomerase FKBP6
Protein Family
UniProt Gene Name
FKBP6
UniProt Synonym Gene Names
FKBP36; Inactive PPIase FKBP6; 36 kDa FKBP; FKBP-36; FKBP-6
UniProt Entry Name
FKBP6_HUMAN

NCBI Description

The protein encoded by this gene is a cis-trans peptidyl-prolyl isomerase that may function in immunoregulation and basic cellular processes involving protein folding and trafficking. This gene is located in a chromosomal region that is deleted in Williams-Beuren syndrome. Defects in this gene may cause male infertility. There are multiple pseudogenes for this gene located nearby on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

FKBP6: PPIases accelerate the folding of proteins. FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Isomerase; EC 5.2.1.8

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: endoplasmic reticulum membrane; cytoplasm; synaptonemal complex; cytosol

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; FK506 binding; Hsp90 protein binding

Biological Process: meiosis; protein peptidyl-prolyl isomerization; protein folding; DNA methylation during gametogenesis; spermatogenesis; RNA-mediated gene silencing; cell differentiation

Research Articles on FKBP6

Similar Products

Product Notes

The FKBP6 fkbp6 (Catalog #AAA6299362) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FKBP6, CT (FKBP6, FKBP36, Peptidyl-prolyl cis-trans isomerase FKBP6, 36kD FK506-binding protein, FK506-binding protein 6, Immunophilin FKBP36, Rotamase) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FKBP6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the FKBP6 fkbp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FKBP6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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