Structure
Pyrvinium pamoate Biochemical
Pyrvinium pamoate
Purity
>98% (HPLC)
Synonyms
Pyrvinium pamoate; Pyrvinium embonate; Pyrvinium pamoate biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=24mg/mL
Target
Casein Kinase
Receptor
Casein Kinase
Chemical Name
Quinolinium, 6-(dimethylamino)-2-[2-(2, 5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-, 4, 4'-methylenebis[3-hydroxy-2-naphthalenecarboxylate](2:1)
SMILES
CN(C)C1=CC2=C([N+](C)=C(/C=C/C3=C(C)N(C4=CC=CC=C4)C(C)=C3)C=C2)C=C1.CN(C)C5=CC6=C([N+](C)=C(/C=C/C7=C(C)N(C8=CC=CC=C8)C(C)=C7)C=C6)C=C5.[O-]C(C9=CC%10=C(C=CC=C%10)C(CC%11=C(O)C(C([O-])=O)=CC%12=C%11C=CC=C%12)=C9O)=O
Molecular Formula
C26H28N3.1/2C23H14O6
CAS Number
3546-41-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Pyrvinium pamoate biochemical
An anthelmintic effective agent for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10nM; binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1alpha kinase activity; inhibits Wnt signaling downstream of beta-catenin, and promotes Pygopus degradation; also is a potent inhibitor of HH signaling by reducing the stability of the Gli family of transcription factors.
Product Categories/Family for Pyrvinium pamoate biochemical
References
1. Thorne CA, et al. Nat Chem Biol. 2010 Nov; 6 (11):829-36.
2. Li B, et al. Cancer Res. 2014 Sep 1; 74 (17):4811-21.
3. Li B, et al. Sci Signal. 2017 Jun 27; 10 (485). pii: eaak9916.
2. Li B, et al. Cancer Res. 2014 Sep 1; 74 (17):4811-21.
3. Li B, et al. Sci Signal. 2017 Jun 27; 10 (485). pii: eaak9916.
Similar Products
Product Notes
The Pyrvinium pamoate (Catalog #AAA3604209) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Pyrvinium pamoate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
