Western Blot (WB)
(FGF22 Antibody (N-term) western blot analysis in MDA-MB231,K562,293,CEM cell line lysates (35ug/lane).This demonstrates the FGF22 antibody detected the FGF22 protein (arrow).)
Rabbit FGF22 Polyclonal Antibody | anti-FGF22 antibody
FGF22 Antibody (N-term)
Western Blot (WB)
(FGF22 Antibody (N-term) western blot analysis in MDA-MB231,K562,293,CEM cell line lysates (35ug/lane).This demonstrates the FGF22 antibody detected the FGF22 protein (arrow).)
Western Blot (WB)
(FGF22 Antibody (N-term) western blot analysis in MDA-MB231,K562,293,CEM cell line lysates (35ug/lane).This demonstrates the FGF22 antibody detected the FGF22 protein (arrow).)
fibroblast growth factor (FGF) family. FGF family members possess
broad mitogenic and cell survival activities and are involved in a
variety of biological processes including embryonic development,
cell growth, morphogenesis, tissue repair, tumor growth and
invasion. The mouse homolog of this gene was found to be
preferentially expressed in the inner root sheath of the hair
follicle, which suggested a role in hair development. [provided by
RefSeq].
Zhang, X., et al. J. Biol. Chem. 281(23):15694-15700(2006)
Beer, H.D., et al. Oncogene 24(34):5269-5277(2005)
Popovici, C., et al. J. Biol. Chem. 279(38):40146-40152(2004)
Umemori, H., et al. Cell 118(2):257-270(2004)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Uniprot Description
FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: Golgi apparatus; extracellular space; cell surface; nucleolus; extracellular region
Molecular Function: growth factor activity; fibroblast growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; insulin receptor signaling pathway; innate immune response; cell differentiation
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Product Notes
The FGF22 fgf22 (Catalog #AAA9213486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-46. The FGF22 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's FGF22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the FGF22 fgf22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGF22, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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