Western Blot (WB)
(Western Blot analysis of SPATA13 in Hela cells using SPATA13 Rabbit pAb at dilution 1/200)
Rabbit anti-Human, Mouse SPATA13 Polyclonal Antibody | anti-SPATA13 antibody
SPATA13 Rabbit pAb
Gene Names
SPATA13; ASEF2; ARHGEF29
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
SPATA13; Polyclonal Antibody; SPATA13 Rabbit pAb; Spermatogenesis associated 13; ASEF2; ARHGEF29; RP11-307N16.3; anti-SPATA13 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.1mg/ml (varies by lot)
Applicable Applications for anti-SPATA13 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC-P: 1:25-1:100
IHC-P: 1:25-1:100
Immunogen
Fusion protein of human SPATA13
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of SPATA13 in Hela cells using SPATA13 Rabbit pAb at dilution 1/200)
Western Blot (WB)
(Western Blot analysis of SPATA13 in Hela cells using SPATA13 Rabbit pAb at dilution 1/200)
Immunohistochemistry (IHC)
(Immunohistochemistry of SPATA13 in paraffin-embedded Human colon cancer tissue using SPATA13 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)
Immunohistochemistry (IHC)
(Immunohistochemistry of SPATA13 in paraffin-embedded Human colon cancer tissue using SPATA13 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)
Related Product Information for anti-SPATA13 antibody
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. Both the ABR and the SH3 domains contribute to maintaining the protein in an inhibited conformation by associating with the C-terminal tail. Binding of these domains to the C-terminal tail inhibits the activity of the protein by blocking a region that is required for its GEF activity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
74,820 Da
NCBI Official Full Name
spermatogenesis-associated protein 13 isoform 1
NCBI Official Synonym Full Names
spermatogenesis associated 13
NCBI Official Symbol
SPATA13
NCBI Official Synonym Symbols
ASEF2; ARHGEF29
NCBI Protein Information
spermatogenesis-associated protein 13; APC-stimulated guanine nucleotide exchange factor 2; adenomatous polyposis coli stimulated exchange factor 2
UniProt Protein Name
Spermatogenesis-associated protein 13
Protein Family
UniProt Gene Name
SPATA13
UniProt Synonym Gene Names
Asef2
UniProt Entry Name
SPT13_HUMAN
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Product Notes
The SPATA13 spata13 (Catalog #AAA4759965) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPATA13 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SPATA13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the SPATA13 spata13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPATA13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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