Rabbit Fatty Acid Binding Protein, Intestinal Polyclonal Antibody | anti-FABP2 antibody

Fatty Acid Binding Protein, Intestinal (FABP)

Cat. Num. AAA612931

• Gene Names: FABP2; FABPI; I-FABP; MGC133132
• Reactivity: Human, Mouse, Porcine, Rat, Sheep
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified immunoglobulin
• Synonyms: Fatty Acid Binding Protein; Intestinal; Polyclonal Antibody; Intestinal (FABP); Anti -Fatty Acid Binding Protein; anti-FABP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Porcine, Rat, Sheep
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human intestinal fatty acid binding protein (I-FABP) of both natural and recombinant origin. Specificity was further assessed by ELISA and Western Blot. No crossreactivities with other FABP types have been detected. Species Crossreactivity: rat, mouse, sheep and porcine
• Purity/Purification: Affinity Purified; Purified immunoglobulin
• Form/Format: Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.

• Applicable Applications for anti-FABP2 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in staining cells containing I-FABP in cells cultured on cover slip (Immunohistochemistry), Western Blot and ELISA.; Dilution: Immunohistochemistry: 1:10; Western Blot: 1:10
• Immunogen: Purified human intestinal fatty acid binding protein
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-FABP2 antibody

Intestinal fatty acid binding protein (I-FABP) is specific localized in the small bowel epithelium. I-FABP is detectable in serum and urine after ischemic injury to the small bowel.

Product Categories/Family for anti-FABP2 antibody

Antibodies; Abs to Fatty Acid Binding Protein

NCBI and Uniprot Product Information

• NCBI GI #: 194097325
• NCBI GeneID: 2169
• NCBI Accession #: NP_000125.2
• NCBI GenBank Nucleotide #: NM_000134.3
• UniProt Accession #: P12104; Q2NKJ1
• Molecular Weight: 15,207 Da
• NCBI Official Full Name: fatty acid-binding protein, intestinal
• NCBI Official Synonym Full Names: fatty acid binding protein 2, intestinal
• NCBI Official Symbol: FABP2
• NCBI Official Synonym Symbols: FABPI; I-FABP; MGC133132
• NCBI Protein Information: fatty acid-binding protein, intestinal; OTTHUMP00000163925; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, intestinal
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP2
• UniProt Synonym Gene Names: FABPI
• UniProt Entry Name: FABPI_HUMAN

NCBI Description

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq]

Uniprot Description

FABP2: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Chromosomal Location of Human Ortholog: 4q28-q31

Cellular Component: cytoplasm

Molecular Function: transporter activity; fatty acid binding

Biological Process: transport; digestion