Rabbit anti-Human EXD2 Polyclonal Antibody | anti-EXD2 antibody

EXD2 Antibody, Biotin conjugated

Cat. Num. AAA7043691

• Gene Names: EXD2; EXDL2; C14orf114
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: EXD2; Polyclonal Antibody; EXD2 Antibody; Biotin conjugated; Exonuclease 3'-5' domain-containing protein 2; Exonuclease 3'-5' domain-like-containing protein 2; anti-EXD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 621

• Applicable Applications for anti-EXD2 antibody: ELISA (EIA)
• Species: Human
• Immunogen: Recombinant human Exonuclease 3'-5' domain-containing protein 2 protein
• Conjugate: Biotin
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-EXD2 antibody

Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

NCBI and Uniprot Product Information

• NCBI GI #: 301129155
• NCBI GeneID: 55218
• NCBI Accession #: NP_001180289.1
• NCBI GenBank Nucleotide #: NM_001193360.1
• UniProt Accession #: Q9NVH0; Q6AWB6; Q8N3D3; B4DIH6; G5E947
• Molecular Weight: 56,346 Da
• NCBI Official Full Name: exonuclease 3'-5' domain-containing protein 2 isoform 1
• NCBI Official Synonym Full Names: exonuclease 3'-5' domain containing 2
• NCBI Official Symbol: EXD2
• NCBI Official Synonym Symbols: EXDL2; C14orf114
• NCBI Protein Information: exonuclease 3'-5' domain-containing protein 2
• UniProt Protein Name: Exonuclease 3'-5' domain-containing protein 2
• Protein Family: Exonuclease 3'-5' domain-containing protein
• UniProt Gene Name: EXD2
• UniProt Entry Name: EXD2_HUMAN

Uniprot Description

EXDL2: Belongs to the EXD2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: cytoplasm; nucleus

Molecular Function: 3'-5' exonuclease activity; protein binding; single-stranded DNA specific 3'-5' exodeoxyribonuclease activity

Biological Process: DNA double-strand break processing; double-strand break repair; double-strand break repair via homologous recombination