Immunohistochemistry (IHC)
()
Rabbit Estrogen Receptor beta Polyclonal Antibody | anti-Esr2 antibody
Estrogen Receptor beta antibody
ICC: 2-4 ug/ml
IF: 0.5 ug/ml
IHC-F: 1-2 ug/ml
IHC-P: 1-2 ug/ml
WB: 1-2 ug/ml
Upon receipt store at -20°C.
Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
()
Immunohistochemistry (IHC)
()
NCBI and Uniprot Product Information
NCBI Description
binds estrogen and mediates transcriptional activation [RGD, Feb 2006]
Uniprot Description
ER-beta: a nuclear hormone receptor and transcription factor. Binds and activated by estrogen. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Eight alternatively-spliced isoforms have been described. Isoform beta-cx lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.
Protein type: DNA-binding; Nuclear receptor
Cellular Component: neuron projection; mitochondrion; cell soma; perinuclear region of cytoplasm; cytoplasm; plasma membrane; perikaryon; nucleus; cilium
Molecular Function: protein binding; peroxisome proliferator activated receptor binding; ligand-dependent nuclear receptor activity; estrogen receptor activity; enzyme binding; DNA binding; hormone binding; zinc ion binding; sequence-specific DNA binding; estrogen response element binding; steroid hormone receptor activity; drug binding; transcription factor activity; steroid binding
Biological Process: prostate gland development; hypothalamus development; behavioral fear response; estrogen receptor signaling pathway; negative regulation of smooth muscle cell proliferation; induction of apoptosis by hormones; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; response to hormone stimulus; neuron migration; negative regulation of transcription from RNA polymerase II promoter; amygdala development; uterus development; response to insecticide; response to organic cyclic substance; response to estradiol stimulus; negative regulation of cell proliferation; learning and/or memory; ovarian follicle development; regulation of transcription, DNA-dependent; positive regulation of epidermal growth factor receptor signaling pathway; regulation of neuron apoptosis; cerebellum development; female gonad development; negative regulation of epithelial cell proliferation; response to nutrient levels; steroid hormone receptor signaling pathway; response to drug; transcription, DNA-dependent; male gonad development; vagina development; Sertoli cell proliferation; response to testosterone stimulus; Sertoli cell development; regulation of cell proliferation; response to genistein; response to ethanol; response to estrogen stimulus; positive regulation of transcription factor activity; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; brain development; response to activity; negative regulation of behavior; response to water deprivation
Research Articles on Esr2
Similar Products
Product Notes
The Esr2 esr2 (Catalog #AAA534283) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Estrogen Receptor beta antibody reacts with Human, Mouse, Non-Human Primate, Rat, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Estrogen Receptor beta can be used in a range of immunoassay formats including, but not limited to, Gel Shift, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB). Gel Shift: 1-5 ul ICC: 2-4 ug/ml IF: 0.5 ug/ml IHC-F: 1-2 ug/ml IHC-P: 1-2 ug/ml WB: 1-2 ug/ml. Researchers should empirically determine the suitability of the Esr2 esr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Estrogen Receptor beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
