Rat Estrogen receptor beta ELISA Kit | Esr2 elisa kit
Rat Estrogen receptor beta ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds estrogen and mediates transcriptional activation [RGD, Feb 2006]
Uniprot Description
ER-beta: a nuclear hormone receptor and transcription factor. Binds and activated by estrogen. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Eight alternatively-spliced isoforms have been described. Isoform beta-cx lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.
Protein type: DNA-binding; Nuclear receptor
Cellular Component: cell soma; cilium; cytoplasm; mitochondrion; neuron projection; nucleus; perikaryon; perinuclear region of cytoplasm; plasma membrane
Molecular Function: DNA binding; drug binding; enzyme binding; estrogen receptor activity; estrogen response element binding; hormone binding; peroxisome proliferator activated receptor binding; protein binding; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; transcription factor activity; zinc ion binding
Biological Process: amygdala development; behavioral fear response; brain development; cerebellum development; estrogen receptor signaling pathway; female gonad development; hypothalamus development; induction of apoptosis by hormones; learning and/or memory; male gonad development; negative regulation of behavior; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of smooth muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; neuron migration; ovarian follicle development; positive regulation of apoptosis; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of vasodilation; prostate gland development; regulation of cell proliferation; regulation of neuron apoptosis; regulation of transcription, DNA-dependent; response to activity; response to drug; response to estradiol stimulus; response to estrogen stimulus; response to ethanol; response to genistein; response to hormone stimulus; response to insecticide; response to nutrient levels; response to organic cyclic substance; response to testosterone stimulus; response to water deprivation; Sertoli cell development; Sertoli cell proliferation; steroid hormone mediated signaling; steroid hormone receptor signaling pathway; transcription from RNA polymerase II promoter; transcription, DNA-dependent; uterus development; vagina development
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Product Notes
The Rat Esr2 esr2 (Catalog #AAA2881502) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881502 ELISA Kit recognizes Rat Esr2. It is sometimes possible for the material contained within the vial of "Estrogen receptor beta, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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