Rabbit anti-Human ERAL1 Polyclonal Antibody | anti-Eral1 antibody

ERAL1, ID (ERAL1, HERA, GTPase Era, mitochondrial, Conserved ERA-like GTPase, ERA-W, ERA-like protein 1)

Cat. Num. AAA6011449

• Gene Names: Eral1; Era; M-ERA; MERA-S; MERA-W; AU019798; 2610524P08Rik; 9130407C09Rik
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ERAL1; Polyclonal Antibody; ID (ERAL1; HERA; GTPase Era; mitochondrial; Conserved ERA-like GTPase; ERA-W; ERA-like protein 1); Anti -ERAL1; anti-Eral1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-Eral1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: ERAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human ERAL1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ERAL1 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ERAL1 antibody detected the ERAL1 protein (arrow).)

Related Product Information for anti-Eral1 antibody

Era is an essential GTPase that is required for proper cell cycle progression and cell division in E. coli. Human homologues have been isolated which have been designated ERAL1A and ERAL1B.

Product Categories/Family for anti-Eral1 antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 18044650
• NCBI GeneID: 57837
• UniProt Accession #: Q9CZU4; Q6NV78; Q8VE60; Q925U1
• Molecular Weight: 48,187 Da
• NCBI Official Full Name: Eral1 protein, partial
• NCBI Official Synonym Full Names: Era (G-protein)-like 1 (E. coli)
• NCBI Official Symbol: Eral1
• NCBI Official Synonym Symbols: Era; M-ERA; MERA-S; MERA-W; AU019798; 2610524P08Rik; 9130407C09Rik
• NCBI Protein Information: GTPase Era, mitochondrial; CEGA; ERA-W; ERA-like GTPase; ERA-like protein 1; conserved ERA-like GTPase; GTP-binding protein era homolog
• UniProt Protein Name: GTPase Era, mitochondrial
• UniProt Gene Name: Eral1
• UniProt Synonym Gene Names: Mera; M-ERA; CEGA
• UniProt Entry Name: ERAL1_MOUSE

Uniprot Description

ERAL1: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly. Belongs to the Era/MnmE GTP-binding protein family. Era subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Cellular Component: intermediate filament cytoskeleton; mitochondrion; membrane; mitochondrial matrix; mitochondrial inner membrane; cytoplasm; intracellular; actin cytoskeleton

Molecular Function: rRNA binding; GTP binding; RNA binding; nucleotide binding; ribosomal small subunit binding

Biological Process: ribosome biogenesis and assembly; ribosomal small subunit assembly and maintenance