Western Blot (WB)
(Anti-Eotaxin antibody, MBS175718, Western blottingLane 1: Recombinant mouse Eotaxin Protein 10ngLane 2: Recombinant mouse Eotaxin Protein 5ngLane 3: Recombinant mouse Eotaxin Protein 2.5ngLane 4: Recombinant mouse Eotaxin Protein 1.25ng)
Rabbit anti-Mouse, Rat Eotaxin Polyclonal Antibody | anti-CCL11 antibody
Anti-Eotaxin antibody
Gene Names
Ccl11; Scya11; eotaxin
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
Eotaxin; Polyclonal Antibody; Anti-Eotaxin antibody; chemokine(C-C motif) ligand 11; C-C motif chemokine 11 antibody; CCL 11 antibody; CCL11 antibody; CCL11_HUMAN antibody; chemokine(C-C motif) ligand 11 antibody; Chemokine C C motif ligand 11 antibody; Chemokine CC Motif Ligand 11 antibody; Chemokine ligand 11 antibody; Eosinophil Chemotactic Protein antibody; Eotaxin antibody; eotaxin-1 antibody; MGC22554 antibody; SCYA 11 antibody; SCYA11 antibody; Small inducible cytokine A11 antibody; Small inducible cytokine subfamily A(Cys Cys) member 11 antibody; small inducible cytokine subfamily A(Cys-Cys); member 11(eotaxin) antibody; Small inducible cytokine subfamily A member 11 antibody; Small-inducible cytokine A11 antibody; anti-CCL11 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
97
Applicable Applications for anti-CCL11 antibody
Western Blot (WB)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Eotaxin (73-93aa CADPKKKWVQDATKHLDQKLQ), identical to the related rat sequence.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti-Eotaxin antibody, MBS175718, Western blottingLane 1: Recombinant mouse Eotaxin Protein 10ngLane 2: Recombinant mouse Eotaxin Protein 5ngLane 3: Recombinant mouse Eotaxin Protein 2.5ngLane 4: Recombinant mouse Eotaxin Protein 1.25ng)
Western Blot (WB)
(Anti-Eotaxin antibody, MBS175718, Western blottingLane 1: Recombinant mouse Eotaxin Protein 10ngLane 2: Recombinant mouse Eotaxin Protein 5ngLane 3: Recombinant mouse Eotaxin Protein 2.5ngLane 4: Recombinant mouse Eotaxin Protein 1.25ng)
Related Product Information for anti-CCL11 antibody
Description: Rabbit IgG polyclonal antibody for Eotaxin(CCL11) detection. Tested with WB in Mouse, Rat.
Background: Eotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
Background: Eotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
10,893 Da
NCBI Official Full Name
Eotaxin
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 11
NCBI Official Symbol
Ccl11
NCBI Official Synonym Symbols
Scya11; eotaxin
NCBI Protein Information
eotaxin; C-C motif chemokine 11; small inducible cytokine A11; small-inducible cytokine A11; eosinophil chemotactic protein; small chemokine (C-C motif) ligand 11
UniProt Protein Name
Eotaxin
Protein Family
UniProt Gene Name
Ccl11
UniProt Synonym Gene Names
Scya11
UniProt Entry Name
CCL11_MOUSE
Uniprot Description
CCL11: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis
Cellular Component: extracellular space; extracellular region; intracellular
Molecular Function: chemokine activity; cytokine activity
Biological Process: regulation of cell shape; positive regulation of angiogenesis; positive regulation of actin filament polymerization; mast cell chemotaxis; eosinophil chemotaxis; actin filament organization; cytoskeleton organization and biogenesis; positive regulation of endothelial cell proliferation; immune response; chemotaxis; inflammatory response; positive regulation of cell migration
Research Articles on CCL11
Similar Products
Product Notes
The CCL11 ccl11 (Catalog #AAA175718) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Eotaxin antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Eotaxin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CCL11 ccl11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Eotaxin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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