Rabbit EMX1 Polyclonal Antibody | anti-EMX1 antibody

EMX1 Polyclonal Antibody

Cat. Num. AAA3007581

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: EMX1; Polyclonal Antibody; EMX1 Polyclonal Antibody; Homeobox protein EMX1; Empty spiracles homolog 1; Empty spiracles-like protein 1; anti-EMX1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: EMX1 polyclonal antibody detects endogenous levels of EMX1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 290

• Applicable Applications for anti-EMX1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding Human EMX1.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of EMX1 polyclonal antibody at 1:500 dilutionLane1:COS-7 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:The Brain tissue lysate of Mouse (40ug) Lane4:C6 whole cell lysate (40ug))

Related Product Information for anti-EMX1 antibody

Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day 10 post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p13.2 and 10q26.1, respectively.

NCBI and Uniprot Product Information

• NCBI GI #: 94536800
• NCBI Accession #: NP_004088.2
• NCBI GenBank Nucleotide #: NP_004088.2
• UniProt Accession #: Q04741
• Molecular Weight: ~ 28kDa
• NCBI Official Full Name: homeobox protein EMX1
• UniProt Protein Name: Homeobox protein EMX1
• Protein Family: Homeobox protein
• UniProt Gene Name: EMX1
• UniProt Entry Name: EMX1_HUMAN

Uniprot Description

EMX1: Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. Belongs to the EMX homeobox family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2p13.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding

Biological Process: response to drug; regulation of transcription, DNA-dependent; in utero embryonic development; brain morphogenesis; cerebral cortex regionalization; cerebral cortex neuron differentiation; post-embryonic development