Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using EI24 Polyclonal Antibody at dilution 1:25)
Rabbit EI24 Polyclonal Antibody | anti-EI24 antibody
EI24 Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using EI24 Polyclonal Antibody at dilution 1:25)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using EI24 Polyclonal Antibody at dilution 1:25)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]
Uniprot Description
EI24: a p53-induced gene that appears to play a role in p53-mediated events. May activate apoptosis and reduce tumor invasiveness. Mutations in its gene have been associated with breast cancer.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Apoptosis
Chromosomal Location of Human Ortholog: 11q24
Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; nuclear membrane; membrane; endoplasmic reticulum; cytoplasm; integral to membrane
Biological Process: response to drug; DNA damage response, signal transduction resulting in induction of apoptosis; apoptosis; autophagy; negative regulation of cell growth; neuromuscular process controlling balance
Research Articles on EI24
Similar Products
Product Notes
The EI24 ei24 (Catalog #AAA2518115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EI24 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EI24 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:10-1:50. Researchers should empirically determine the suitability of the EI24 ei24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EI24, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
