Rabbit EGFL6 Polyclonal Antibody | anti-EGFL6 antibody

Anti-EGFL6 Antibody

Cat. Num. AAA416095

• Gene Names: EGFL6; W80; MAEG
• Reactivity: Human. Predicted: Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: EGFL6; Polyclonal Antibody; Anti-EGFL6 Antibody; anti-EGFL6 antibody

• Host: Rabbit
• Reactivity: Human. Predicted: Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Affinity purified
• Form/Format: Liquid
• Concentration: 100ug/100ul (varies by lot)
• Sequence Length: 2282

• Applicable Applications for anti-EGFL6 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA titer: 1:20,000-1:80,000; Western blot analysis: 1:1,000-1:2,000; Immunohistochemistry: 1:100-1:500; Optimal dilutions/concentrations should be determined by the end user.
• Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
• Immunogen: Rabbit polyclonal EGFL6 (1) antibody was raised against a recombinated human EGFL6 protein 30-219aa (BC038587).
• Preparation and Storage: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

Related Product Information for anti-EGFL6 antibody

This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]

References

(1) Oberauer,R., Rist,W., Lenter,M.C., et al. EGFL6 is increasingly expressed in human obesity and promotes proliferation of adipose tissue-derived stromal vascular cells. Mol. Cell. Biochem. 343 (1-2), 257-269 (2010) Avoid repeated.

NCBI and Uniprot Product Information

• NCBI GI #: 24047223
• NCBI GeneID: 25975
• Molecular Weight: 61,388 Da
• NCBI Official Full Name: Homo sapiens EGF-like-domain, multiple 6, mRNA
• NCBI Official Synonym Full Names: EGF-like-domain, multiple 6
• NCBI Official Symbol: EGFL6
• NCBI Official Synonym Symbols: W80; MAEG
• NCBI Protein Information: epidermal growth factor-like protein 6; EGF repeat-containing protein 6; EGF-like protein 6; MAM and EGF domain containing; MAM and EGF domains-containing gene protein
• UniProt Protein Name: Epidermal growth factor-like protein 6
• Protein Family: Epidermal growth factor-like protein
• UniProt Gene Name: EGFL6
• UniProt Entry Name: EGFL6_HUMAN

NCBI Description

This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]

Uniprot Description

EGFL6: May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly. Belongs to the nephronectin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: Xp22

Cellular Component: extracellular space; membrane; basement membrane

Molecular Function: integrin binding; calcium ion binding

Biological Process: extracellular matrix organization and biogenesis; multicellular organismal development; cell cycle; cell differentiation; cell adhesion