Western Blot (WB)
(Anti-EGF antibody, MBS175142, Western blottingLane 1: Recombinant Mouse EGF Protein 10ngLane 2: Recombinant Mouse EGF Protein 5ngLane 3: Recombinant Mouse EGF Protein 2.5ng )
Rabbit anti-Mouse EGF Polyclonal Antibody | anti-EGF antibody
Anti-EGF antibody
Western Blot (WB)
(Anti-EGF antibody, MBS175142, Western blottingLane 1: Recombinant Mouse EGF Protein 10ngLane 2: Recombinant Mouse EGF Protein 5ngLane 3: Recombinant Mouse EGF Protein 2.5ng )
Western Blot (WB)
(Anti-EGF antibody, MBS175142, Western blottingLane 1: Recombinant Mouse EGF Protein 10ngLane 2: Recombinant Mouse EGF Protein 5ngLane 3: Recombinant Mouse EGF Protein 2.5ng )
Immunohistochemistry (IHC)
(Anti-EGF antibody, MBS175142, IHC(P)IHC(P): Mouse Intestine Tissue )
Immunohistochemistry (IHC)
(Anti-EGF antibody, MBS175142, IHC(P)IHC(P): Mouse Intestine Tissue )
Background: Epidermal growth factor(EGF) is a growth factor that plays an important role in the regulation of cell growth, proliferation and differentiation by binding to its receptor EGFR. EGF locus is mapped to 4q21-4qter. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bones. EGF results in cellular proliferation, differentiation, and survival while plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity.
NCBI and Uniprot Product Information
Uniprot Description
EGF: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4); also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hormone; Ligand, receptor tyrosine kinase; Membrane protein, integral
Cellular Component: extracellular space; membrane; lysosomal membrane; integral to membrane; plasma membrane; intracellular
Molecular Function: protein binding; growth factor activity; calcium ion binding; epidermal growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; peptidyl-tyrosine phosphorylation; positive regulation of mitosis; activation of MAPKK activity; positive regulation of transcription, DNA-dependent; regulation of protein transport; positive regulation of MAP kinase activity; regulation of protein secretion; branching morphogenesis of a tube; positive regulation of epidermal growth factor receptor activity; positive regulation of cell proliferation; negative regulation of secretion; angiogenesis; regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphorylation; positive regulation of granule cell precursor proliferation; STAT protein nuclear translocation; positive regulation of DNA binding
Research Articles on EGF
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Product Notes
The EGF egf (Catalog #AAA175142) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-EGF antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EGF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the EGF egf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EGF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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