Rabbit anti-Human, Mouse DUOX1 Polyclonal Antibody | anti-DUOX1 antibody
DUOX1 Antibody
Gene Names
DUOX1; LNOX1; THOX1; NOXEF1
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DUOX1; Polyclonal Antibody; DUOX1 Antibody; Dual oxidase 1; Dual oxidase 1 precursor; EC 1.11.1; EC 1.6.3.1; Flavoprotein NADPH oxidase; Large NOX 1; LNOX1; Long NOX 1; MGC138840; MGC138841; NADPH thyroid oxidase 1; Nicotinamide adenine dinucleotide phosphate oxidase; NOXEF1; THOX1; Thyroid oxidase 1; anti-DUOX1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
DUOX1 Antibody detects endogenous levels of DUOX1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-DUOX1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human DUOX1.
Conjugation
Unconjugated
Similarity
In the N-terminal section; belongs to the peroxidase family.
Post Translational Modifications
N-glycosylated.
Subunit Structure
Interacts with TXNDC11, TPO and CYBA.
Tissue Specificity
Expressed in thyrocytes and tracheal surface epithelial cells (at protein level). Expressed in thyroid, trachea, bronchium, and to a lower extent, in placenta, testis, prostate, pancreas and heart.
Function
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Note
Localizes to the apical membrane of epithelial cells.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-DUOX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
137,604 Da
NCBI Official Full Name
dual oxidase 1
NCBI Official Synonym Full Names
dual oxidase 1
NCBI Official Symbol
DUOX1
NCBI Official Synonym Symbols
LNOX1; THOX1; NOXEF1
NCBI Protein Information
dual oxidase 1; NADPH thyroid oxidase 1; flavoprotein NADPH oxidase; large NOX 1; long NOX 1; nicotinamide adenine dinucleotide phosphate oxidase
UniProt Protein Name
Dual oxidase 1
Protein Family
UniProt Gene Name
DUOX1
UniProt Synonym Gene Names
DUOX; LNOX1; THOX1
UniProt Entry Name
DUOX1_HUMAN
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Product Notes
The DUOX1 duox1 (Catalog #AAA9630787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DUOX1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DUOX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the DUOX1 duox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUOX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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