Rabbit DRD5 Polyclonal Antibody | anti-DRD5 antibody

DRD5 Antibody

Cat. Num. AAA9607867

• Gene Names: DRD5; DBDR; DRD1B; DRD1L2
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: DRD5; Polyclonal Antibody; DRD5 Antibody; D(1B) dopamine receptor; D(5) dopamine receptor; D1 beta dopamine receptor; D1B dopamine receptor; D1beta dopamine receptor; D5 dopamine receptor; DBDR; Dopamine D5 receptor; Dopamine receptor D1B; dopamine receptor D5; DRD 1B; DRD 5; DRD1B; DRD1L2; DRD5_HUMAN; MGC10601; anti-DRD5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: DRD5 antibody detects endogenous levels of total DRD5
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 477

• Applicable Applications for anti-DRD5 antibody: Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: A synthesized peptide derived from human DRD5
• Subcellular Location: Cell Membrane
• Tissue Specificity: Neuron-specific, localized primarily within limbic regions of the brain.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts of Op9 lysate, using DRD5 antibody. The lane on the left is treated with the antigen-specific peptide.)

Immunohistochemistry (IHC)

(MBS9607867 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

Related Product Information for anti-DRD5 antibody

Description: This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
Function: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Similarity: Belongs to the G-protein coupled receptor 1 family.

NCBI and Uniprot Product Information

• NCBI GI #: 4503391
• NCBI GeneID: 1816
• NCBI Accession #: NP_000789.1
• NCBI GenBank Nucleotide #: NM_000798.4
• UniProt Accession #: P21918; Q8NEQ8; B2R9S3
• Molecular Weight: Observed: 53 kDa; Predicted: 53 kDa
• NCBI Official Full Name: D(1B) dopamine receptor
• NCBI Official Synonym Full Names: dopamine receptor D5
• NCBI Official Symbol: DRD5
• NCBI Official Synonym Symbols: DBDR; DRD1B; DRD1L2
• NCBI Protein Information: D(1B) dopamine receptor
• UniProt Protein Name: D(1B) dopamine receptor
• Protein Family: D(1B) dopamine receptor
• UniProt Gene Name: DRD5
• UniProt Synonym Gene Names: DRD1B; DRD1L2

NCBI Description

This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]

Uniprot Description

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.