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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human bladder cancer using MBS7044237 at dilution 1:100)

Rabbit anti-Human DRAM2 Polyclonal Antibody | anti-DRAM2 antibody

DRAM2 Antibody

Gene Names
DRAM2; CORD21; PRO180; TMEM77; WWFQ154
Reactivity
Human
Applications
ELISA, Immunofluorescence, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
DRAM2; Polyclonal Antibody; DRAM2 Antibody; DNA damage-regulated autophagy modulator protein 2; Transmembrane protein 77; TMEM77; PSEC0031; UNQ154/PRO180; anti-DRAM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
266
Applicable Applications for anti-DRAM2 antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IF: 1:50-1:200
IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human DNA damage-regulated autophagy modulator protein 2 protein (C-85AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-241076
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human bladder cancer using MBS7044237 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human bladder cancer using MBS7044237 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7044237 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human heart tissue using MBS7044237 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of mcf-7 cells using MBS7044237 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of mcf-7 cells using MBS7044237 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-DRAM2 antibody
Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,766 Da
NCBI Official Full Name
DNA damage-regulated autophagy modulator protein 2
NCBI Official Synonym Full Names
DNA damage regulated autophagy modulator 2
NCBI Official Symbol
DRAM2
NCBI Official Synonym Symbols
CORD21; PRO180; TMEM77; WWFQ154
NCBI Protein Information
DNA damage-regulated autophagy modulator protein 2
UniProt Protein Name
DNA damage-regulated autophagy modulator protein 2
UniProt Gene Name
DRAM2
UniProt Synonym Gene Names
TMEM77
UniProt Entry Name
DRAM2_HUMAN

Uniprot Description

TMEM77: Induces apoptotic cell death when coexpressed with DRAM1. Belongs to the DRAM/TMEM150 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: apical plasma membrane; cytoplasm; Golgi apparatus; intracellular membrane-bound organelle; lysosome; photoreceptor inner segment

Biological Process: photoreceptor cell maintenance; regulation of autophagy; visual perception

Disease: Cone-rod Dystrophy 21

Research Articles on DRAM2

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Product Notes

The DRAM2 dram2 (Catalog #AAA7044237) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DRAM2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DRAM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC). Recommended dilution: IF: 1:50-1:200 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the DRAM2 dram2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRAM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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