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Western Blot (WB) (Western Blotting Analysis: Representative lot data. Human placenta tissue lysate was probed with DRAM2 (1ug/ml). Proteins were visualized using a Goat Mouse IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates DRAM2 (~29kD).)

Mouse anti-Human DRAM2 Monoclonal Antibody | anti-DRAM2 antibody

DRAM2 (DNA Damage-regulated Autophagy Modulator Protein 2, Transmembrane Protein 77, TMEM77, PSEC0031, UNQ154/PRO180) (MaxLight 405)

Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
DRAM2; Monoclonal Antibody; DRAM2 (DNA Damage-regulated Autophagy Modulator Protein 2; Transmembrane Protein 77; TMEM77; PSEC0031; UNQ154/PRO180) (MaxLight 405); anti-DRAM2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
13A175
Specificity
Recognizes human DRAM2.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Sequence Length
266
Applicable Applications for anti-DRAM2 antibody
Western Blot (WB)
Immunogen
Synthetic linear peptide corresponding to human DRAM2.
Conjugate
MaxLight405
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Western Blot (WB)

(Western Blotting Analysis: Representative lot data. Human placenta tissue lysate was probed with DRAM2 (1ug/ml). Proteins were visualized using a Goat Mouse IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates DRAM2 (~29kD).)

Western Blot (WB) (Western Blotting Analysis: Representative lot data. Human placenta tissue lysate was probed with DRAM2 (1ug/ml). Proteins were visualized using a Goat Mouse IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates DRAM2 (~29kD).)
Product Categories/Family for anti-DRAM2 antibody
References
1. Park, S.M., et al. (2009). Biochem Biophys Res Commun. 390(4):1340-1344. 2. O'Prey, J., et al. (2009). Cell Cycle. 8(14): 2260-2265.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29
NCBI Official Full Name
DNA damage-regulated autophagy modulator protein 2 isoform a
UniProt Protein Name
DNA damage-regulated autophagy modulator protein 2
UniProt Gene Name
DRAM2
UniProt Synonym Gene Names
TMEM77
UniProt Entry Name
DRAM2_HUMAN

Uniprot Description

TMEM77: Induces apoptotic cell death when coexpressed with DRAM1. Belongs to the DRAM/TMEM150 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; lysosome; lysosomal membrane; cytoplasm; integral to membrane

Biological Process: apoptosis; regulation of autophagy

Disease: Cone-rod Dystrophy 21

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Product Notes

The DRAM2 dram2 (Catalog #AAA6245182) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DRAM2 (DNA Damage-regulated Autophagy Modulator Protein 2, Transmembrane Protein 77, TMEM77, PSEC0031, UNQ154/PRO180) (MaxLight 405) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DRAM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DRAM2 dram2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRAM2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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