Immunohistochemistry (IHC)
(Anti-DNAJC5 / CSP antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Goat DNAJC5 / CSP Polyclonal Antibody | anti-DNAJC5 antibody
Goat Polyclonal to Human DNAJC5 / CSP
Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 20kD band observed in Human Brain (Cerebellum) lysates (calculated MW of 22.1kD according to NP_058055.1). Recommended concentration: 0.5-1.5 ug/ml.
Immunohistochemistry (IHC)
(Anti-DNAJC5 / CSP antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-DNAJC5 / CSP antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(DNAJC5 antibody (0.5 ug/ml) staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(DNAJC5 antibody (0.5 ug/ml) staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010]
Uniprot Description
DNAJC5: a cysteine string protein that inhibits N-type calcium channels which is blocked by huntingtin mutants. May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings. Modulates the maturation of cystic fibrosis transmembrane conductance regulator. Two splice-variant isoforms have been described.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component: synaptic vesicle; mitochondrion; membrane; lysosomal membrane; melanosome; plasma membrane
Molecular Function: ATP-dependent protein binding; glycoprotein binding
Biological Process: regulated secretory pathway; synaptic transmission; synaptic vesicle exocytosis; exocytosis; neurotransmitter secretion; negative regulation of neuron apoptosis
Research Articles on DNAJC5
Similar Products
Product Notes
The DNAJC5 dnajc5 (Catalog #AAA248450) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human DNAJC5 / CSP reacts with Gibbon, Bovine, Chimpanzee, Chicken, Dog, Guinea pig, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJC5 / CSP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:64000), IHC-P (5 ug/ml), WB (0.5 - 1.5 ug/ml) Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 20kD band observed in Human Brain (Cerebellum) lysates (calculated MW of 22.1kD according to NP_058055.1). Recommended concentration: 0.5-1.5 ug/ml. Researchers should empirically determine the suitability of the DNAJC5 dnajc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJC5 / CSP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
