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Western Blot (WB) (Western Blot analysis of LOVO cells using CSP Polyclonal Antibody)

Rabbit DNAJC5 Polyclonal Antibody | anti-DNAJC5 antibody

DNAJC5 Antibody

Gene Names
DNAJC5; CSP; NCL; CLN4; CLN4B; DNAJC5A
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DNAJC5; Polyclonal Antibody; DNAJC5 Antibody; CSP; DnaJ homolog subfamily C member 5; Cysteine string protein; anti-DNAJC5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Applicable Applications for anti-DNAJC5 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:10000
Immunogen
Synthesized peptide derived from the C-terminal region of human CSP.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of LOVO cells using CSP Polyclonal Antibody)

Western Blot (WB) (Western Blot analysis of LOVO cells using CSP Polyclonal Antibody)
Product Categories/Family for anti-DNAJC5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,149 Da
NCBI Official Full Name
dnaJ homolog subfamily C member 5
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily C, member 5
NCBI Official Symbol
DNAJC5
NCBI Official Synonym Symbols
CSP; NCL; CLN4; CLN4B; DNAJC5A
NCBI Protein Information
dnaJ homolog subfamily C member 5; cysteine string protein alpha
UniProt Protein Name
DnaJ homolog subfamily C member 5
Protein Family
UniProt Gene Name
DNAJC5
UniProt Synonym Gene Names
CSP; CSP
UniProt Entry Name
DNJC5_HUMAN

NCBI Description

This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010]

Uniprot Description

DNAJC5: a cysteine string protein that inhibits N-type calcium channels which is blocked by huntingtin mutants. May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings. Modulates the maturation of cystic fibrosis transmembrane conductance regulator. Two splice-variant isoforms have been described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: synaptic vesicle; membrane; mitochondrion; lysosomal membrane; plasma membrane; melanosome

Molecular Function: ATP-dependent protein binding; glycoprotein binding

Biological Process: regulated secretory pathway; synaptic transmission; synaptic vesicle exocytosis; exocytosis; neurotransmitter secretion; negative regulation of neuron apoptosis

Research Articles on DNAJC5

Similar Products

Product Notes

The DNAJC5 dnajc5 (Catalog #AAA7116177) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNAJC5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJC5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:10000. Researchers should empirically determine the suitability of the DNAJC5 dnajc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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