Western Blot (WB)
(WB Suggested Anti-Dnajb1 AntibodyTitration: 1.0 ug/mlPositive Control: Mouse Liver)
Rabbit Dnajb1 Polyclonal Antibody | anti-DNAJB1 antibody
Dnajb1 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-Dnajb1 AntibodyTitration: 1.0 ug/mlPositive Control: Mouse Liver)
Western Blot (WB)
(WB Suggested Anti-Dnajb1 AntibodyTitration: 1.0 ug/mlPositive Control: Mouse Liver)
Target Description: Dnajb1 interacts with HSP70 and can stimulate its ATPase activity. It stimulates the association between HSC70 and HIP.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. The encoded protein may also inhibit apoptosis. Peritoneal macrophages derived from homozygous knockout mice for this gene exhibit impaired heat tolerance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Uniprot Description
HSP40: a chaperone protein that translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Interacts with DNAJC3. Interacts with SRPK1.
Protein type: Chaperone; Nucleolus
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: ATPase activator activity; ATPase binding; chaperone binding; Hsp70 protein binding; unfolded protein binding
Biological Process: chaperone cofactor-dependent protein folding; positive regulation of ATPase activity; protein folding
Research Articles on DNAJB1
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Product Notes
The DNAJB1 dnajb1 (Catalog #AAA3211867) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dnajb1 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's Dnajb1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DNAJB1 dnajb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: VFKDVIRPGM RRKVPGEGLP LPKTPEKRGD LVIEFEVIFP ERIPVSSRTI. It is sometimes possible for the material contained within the vial of "Dnajb1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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