Rabbit anti-Human, Mouse DHRS3 Polyclonal Antibody | anti-DHRS3 antibody
DHRS3 Antibody
IHC: 1:20-1:200
IF: 1:50-1:200
Western Blot (WB)
(Western blotAll lanes: DHRS3 antibody at 6ug/ml+Mouse kidney tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 34,19 kDaObserved band size: 34 kDa)
Western Blot (WB)
(Western blotAll lanes: DHRS3 antibody at 0.8ug/mlLane 1: A375 whole cell lysateLane 2: Mouse liver tissueLane 3: Mouse spleen tissueLane 4: HL60 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 34, 19 kDaObserved band size: 19 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS7003252 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7003252 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7003252 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7003252 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of A375 cells using MBS7003252 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7003252 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]
Uniprot Description
DHRS3: Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; EC 1.1.1.300; Cofactor and Vitamin Metabolism - retinol; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.1
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: electron carrier activity; nucleotide binding; retinol dehydrogenase activity
Biological Process: negative regulation of retinoic acid receptor signaling pathway; palate development; phototransduction, visible light; regulation of ossification; retinoid metabolic process; retinol metabolic process; visual perception
Research Articles on DHRS3
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Product Notes
The DHRS3 dhrs3 (Catalog #AAA7003252) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DHRS3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DHRS3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the DHRS3 dhrs3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DHRS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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