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Rabbit DERLIN-1 Polyclonal Antibody | anti-DERLIN-1 antibody

DERLIN-1 Antibody HRP Conjugated

Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Purified by Protein A
Synonyms
DERLIN-1; Polyclonal Antibody; DERLIN-1 Antibody HRP Conjugated; Derlin1; Derlin 1; DER1; DER-1; DER 1; DERL1_HUMAN; anti-DERLIN-1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A
Form/Format
10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% Gentamicin.
Concentration
1mgml (varies by lot)
Applicable Applications for anti-DERLIN-1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC: 1:100-500
Conjugation
HRP
Immunogen
KLH conjugated synthetic peptide aa 120-170 251 derived from human DERLIN-1
Preparation and Storage
Store at 4 degree C for 12 months.
Related Product Information for anti-DERLIN-1 antibody
Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.
Product Categories/Family for anti-DERLIN-1 antibody

NCBI and Uniprot Product Information

NCBI GeneID
UniProt Accession #
UniProt Protein Name
Derlin-1
Protein Family
UniProt Gene Name
DERL1
UniProt Synonym Gene Names
DER1
UniProt Entry Name
DERL1_HUMAN

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Product Notes

The DERLIN-1 derl1 (Catalog #AAA9460340) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DERLIN-1 Antibody HRP Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DERLIN-1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC: 1:100-500. Researchers should empirically determine the suitability of the DERLIN-1 derl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DERLIN-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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