Western Blot (WB)
(Western Blot analysis of DEFA6 expression in transfected 293T cell line by MBS641143. Lane 1: DEFA6 transfected lysate (11kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human DEFA6 Polyclonal Antibody | anti-DEFA6 antibody
DEFA6 (Defensin-6, Defensin, alpha 6, DEF6)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of DEFA6 expression in transfected 293T cell line by MBS641143. Lane 1: DEFA6 transfected lysate (11kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of DEFA6 expression in transfected 293T cell line by MBS641143. Lane 1: DEFA6 transfected lysate (11kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Jul 2008]
Uniprot Description
defensin, alpha 6: Has very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1. Belongs to the alpha-defensin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8p23.1
Cellular Component: extracellular space; Golgi lumen; extracellular region
Biological Process: killing of cells of another organism; antibacterial humoral response; innate immune response; defense response to fungus
Research Articles on DEFA6
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Product Notes
The DEFA6 defa6 (Catalog #AAA641143) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DEFA6 (Defensin-6, Defensin, alpha 6, DEF6) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEFA6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the DEFA6 defa6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRTLTILTAV LLVALQAKAE PLQAEDDPLQ AKAYEADAQE QRGANDQDFA VSFAEDASSS LRALGSTRAF TCHCRRSCYS TEYSYGTCTV MGINHRFCCL. It is sometimes possible for the material contained within the vial of "DEFA6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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