Western Blot (WB)
(Western blot analysis of extracts from COS-7, using DDHD2 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit DDHD2 Polyclonal Antibody | anti-DDHD2 antibody
DDHD2 Antibody
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Western Blot (WB)
(Western blot analysis of extracts from COS-7, using DDHD2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from COS-7, using DDHD2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HEK-293 cells, using DDHD2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HEK-293 cells, using DDHD2 Antibody. The lane on the left was treated with blocking peptide.)
Subunit Structure: Forms homooligomers and, to a much smaller extent, heterooligomers with DDHD1.
Similarity: SAM and DDHD domains together are required for phospholipid binding. Belongs to the PA-PLA1 family.
NCBI and Uniprot Product Information
Predicted: 82 kDa
NCBI Description
This gene encodes a phospholipase enzyme containing sterile-alpha-motif (SAM), WWE, and DDHD domains. This protein participates in membrane trafficking between the endoplastic reticulum and the Golgi body. Mutations in this gene can cause autosomal recessive spastic paraplegia 54. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
DDHD2: Phospholipase that hydrolyzes preferentially phosphatidic acid and phosphatidylethanolamine. May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. Belongs to the PA-PLA1 family.
Protein type: EC 3.1.1.-; Hydrolase
Chromosomal Location of Human Ortholog: 8p11.23
Cellular Component: COPII-coated ER to Golgi transport vesicle; cytosol; endoplasmic reticulum-Golgi intermediate compartment; membrane; microtubule organizing center
Molecular Function: metal ion binding; phospholipase activity; triacylglycerol lipase activity
Biological Process: ER to Golgi vesicle-mediated transport; locomotory behavior; phosphatidic acid biosynthetic process; triglyceride catabolic process; visual learning
Disease: Spastic Paraplegia 54, Autosomal Recessive
Research Articles on DDHD2
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Product Notes
The DDHD2 ddhd2 (Catalog #AAA9611683) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDHD2 Antibody reacts with Human, Mouse, Rat, Monkey Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's DDHD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the DDHD2 ddhd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDHD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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