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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS1497584 at dilution 1:100)

Rabbit anti-Human DDB1- and CUL4-associated factor 7 Polyclonal Antibody | anti-DCAF7 antibody

Rabbit anti-human DDB1- and CUL4-associated factor 7 polyclonal Antibody(DCAF7)

Gene Names
DCAF7; AN11; HAN11; WDR68; SWAN-1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
DDB1- and CUL4-associated factor 7; Polyclonal Antibody; Rabbit anti-human DDB1- and CUL4-associated factor 7 polyclonal Antibody(DCAF7); WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; DCAF7; HAN11; WDR68; anti-DCAF7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
342
Applicable Applications for anti-DCAF7 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human DDB1- and CUL4-associated factor 7 protein(1-342aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160914 / sc-160915
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS1497584 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS1497584 at dilution 1:100)
Related Product Information for anti-DCAF7 antibody
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,340 Da
NCBI Official Full Name
DDB1- and CUL4-associated factor 7
NCBI Official Synonym Full Names
DDB1 and CUL4 associated factor 7
NCBI Official Symbol
DCAF7
NCBI Official Synonym Symbols
AN11; HAN11; WDR68; SWAN-1
NCBI Protein Information
DDB1- and CUL4-associated factor 7
UniProt Protein Name
DDB1- and CUL4-associated factor 7
UniProt Gene Name
DCAF7
UniProt Synonym Gene Names
HAN11; WDR68
UniProt Entry Name
DCAF7_HUMAN

NCBI Description

This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot Description

WDR68: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: cytoplasm; nuclear matrix; nucleoplasm; protein complex

Molecular Function: protein binding

Biological Process: multicellular organismal development; protein ubiquitination

Research Articles on DCAF7

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Product Notes

The DCAF7 dcaf7 (Catalog #AAA1497584) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human DDB1- and CUL4-associated factor 7 polyclonal Antibody(DCAF7) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DDB1- and CUL4-associated factor 7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the DCAF7 dcaf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDB1- and CUL4-associated factor 7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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