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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DARS Polyclonal Antibody at dilution of 1:25(×200))

Rabbit DARS Polyclonal Antibody | anti-DARS antibody

DARS Polyclonal Antibody

Gene Names
DARS1; DARS; HBSL; aspRS
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
DARS; Polyclonal Antibody; DARS Polyclonal Antibody; Aspartate tRNA ligase 1 cytoplasmic; Aspartate tRNA ligase; Aspartate--tRNA ligase; Aspartyl tRNA synthetase; Aspartyl tRNA synthetase cytoplasmic; Aspartyl-tRNA synthetase; AspRS; Cell proliferation inducing gene 40 protein; Cell proliferation inducing protein 40; Cell proliferation-inducing gene 40 protein; Cytoplasmic; Dars; DKFZp781B11202; MGC111579; SYDC; anti-DARS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.9mg/mL (varies by lot)
Sequence Length
401
Applicable Applications for anti-DARS antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:30-1:150
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human DARS
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DARS Polyclonal Antibody at dilution of 1:25(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DARS Polyclonal Antibody at dilution of 1:25(×200))
Related Product Information for anti-DARS antibody
This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-DARS antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
aspartate--tRNA ligase, cytoplasmic isoform 2
NCBI Official Synonym Full Names
aspartyl-tRNA synthetase 1
NCBI Official Symbol
DARS1
NCBI Official Synonym Symbols
DARS; HBSL; aspRS
NCBI Protein Information
aspartate--tRNA ligase, cytoplasmic
UniProt Protein Name
Aspartate--tRNA ligase, cytoplasmic
UniProt Gene Name
DARS
UniProt Synonym Gene Names
AspRS
UniProt Entry Name
SYDC_HUMAN

NCBI Description

This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Uniprot Description

DARS: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Belongs to the class-II aminoacyl-tRNA synthetase family.

Protein type: Translation; EC 6.1.1.12; Ligase

Chromosomal Location of Human Ortholog: 2q21.3

Cellular Component: membrane; cytoplasm; cytosol

Molecular Function: protein binding; aspartate-tRNA ligase activity; ATP binding; aminoacylase activity

Biological Process: tRNA aminoacylation for protein translation; translation; aspartyl-tRNA aminoacylation; protein complex assembly; gene expression

Disease: Hypomyelination With Brainstem And Spinal Cord Involvement And Leg Spasticity

Research Articles on DARS

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Product Notes

The DARS dars (Catalog #AAA2560531) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DARS Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DARS can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:30-1:150 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the DARS dars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DARS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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