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Knockout Validation (Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: GR knockout Hela cell lysate; Predicted MW: 56kd Observed MW: 56kd Primary Ab: 3ug/ml Rabbit Anti-Human GR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))

Rabbit anti-Human Glutathione Reductase (GR) Polyclonal Antibody | anti-GR antibody

Biotin-Linked Polyclonal Antibody to Glutathione Reductase (GR)

Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Synonyms
Glutathione Reductase (GR); Polyclonal Antibody; Biotin-Linked Polyclonal Antibody to Glutathione Reductase (GR); GSR; GLUR; GRD1; Glutathione reductase; mitochondrial; anti-GR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Concentration
500ug/ml (varies by lot)
Sequence Length
410
Applicable Applications for anti-GR antibody
Western Blot (WB), Immunohistochemistry (IHC)
Conjugation
Biotin
Cross Reactivity
Human
Immunogen
GR (Met44~Arg522)

Knockout Validation

(Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: GR knockout Hela cell lysate; Predicted MW: 56kd Observed MW: 56kd Primary Ab: 3ug/ml Rabbit Anti-Human GR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))

Knockout Validation (Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: GR knockout Hela cell lysate; Predicted MW: 56kd Observed MW: 56kd Primary Ab: 3ug/ml Rabbit Anti-Human GR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,301 Da
NCBI Official Full Name
glutathione reductase
NCBI Official Synonym Full Names
glutathione-disulfide reductase
NCBI Official Symbol
Gsr
NCBI Protein Information
glutathione reductase
UniProt Protein Name
Glutathione reductase
Protein Family
UniProt Gene Name
Gsr
UniProt Synonym Gene Names
GR; GRase

NCBI Description

catalyzes the conversion of glutathione and NADP+ to glutathione disulfide and NADPH + H+; may play a role in spermatogenesis [RGD, Feb 2006]

Uniprot Description

GSR: Maintains high levels of reduced glutathione in the cytosol

Protein type: EC 1.8.1.7; Other Amino Acids Metabolism - glutathione; Oxidoreductase

Chromosomal Location of Human Ortholog: 16q12.3

Cellular Component: cell; cytosol; external side of plasma membrane; mitochondrion

Molecular Function: FAD binding; glutathione binding; glutathione-disulfide reductase activity; NADP binding; protein homodimerization activity

Biological Process: aging; cell redox homeostasis; glutathione metabolic process; response to activity; response to cadmium ion; response to ethanol; response to iron(III) ion; response to nicotine; response to oxidative stress; response to vitamin A; selenium compound metabolic process; spermatogenesis

Research Articles on GR

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Product Notes

The GR gsr (Catalog #AAA2093134) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Biotin-Linked Polyclonal Antibody to Glutathione Reductase (GR) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glutathione Reductase (GR) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the GR gsr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutathione Reductase (GR), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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