Rabbit anti-Human DAPK2 Polyclonal Antibody | anti-DAPK2 antibody

DAPK2 Polyclonal Antibody

Cat. Num. AAA2566791

• Gene Names: DAPK2; DRP1; DRP-1
• Reactivity: Human
• Applications: Immunofluorescence
• Purity: Affinity purification
• Synonyms: DAPK2; Polyclonal Antibody; DAPK2 Polyclonal Antibody; DRP-1; DRP1; anti-DAPK2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 1mg/mL (varies by lot)

• Applicable Applications for anti-DAPK2 antibody: Immunofluorescence (IF)
• Application Notes: IF: 1:50-1:200
• Immunogen: A synthetic peptide of human DAPK2 (NP_0551412)
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunofluorescence (IF)

(Immunofluorescence analysis of U2OS cells using DAPK2 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Related Product Information for anti-DAPK2 antibody

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.

Product Categories/Family for anti-DAPK2 antibody

Cancer; Cell Biology; Polyclonal Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 14670383
• NCBI GeneID: 23604
• NCBI Accession #: NP_055141.2
• NCBI GenBank Nucleotide #: NM_014326.3
• UniProt Accession #: Q9UIK4; O75892; Q24JS1
• Molecular Weight: 42,898 Da
• NCBI Official Full Name: death-associated protein kinase 2
• NCBI Official Synonym Full Names: death-associated protein kinase 2
• NCBI Official Symbol: DAPK2
• NCBI Official Synonym Symbols: DRP1; DRP-1
• NCBI Protein Information: death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1 beta isoform
• UniProt Protein Name: Death-associated protein kinase 2
• Protein Family: Death-associated protein kinase
• UniProt Gene Name: DAPK2
• UniProt Synonym Gene Names: DAP kinase 2; DRP-1
• UniProt Entry Name: DAPK2_HUMAN

NCBI Description

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]

Uniprot Description

DAPK2: an ubiquitously expressed protein kinase of the DAPK family. Activated by Ca(2+)/calmodulin. Contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain. Overexpression induces apoptosis. Expressed at high levels in heart, lung and skeletal muscle.

Protein type: Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: cytoplasm; cytoplasmic vesicle

Molecular Function: calmodulin binding; identical protein binding; protein serine/threonine kinase activity; protein binding; calmodulin-dependent protein kinase activity; ATP binding

Biological Process: regulation of apoptosis; apoptosis; protein amino acid autophosphorylation; regulation of autophagy; protein amino acid phosphorylation; anoikis