Immunohistochemistry (IHC)
(Anti-DEFB1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Rabbit anti-Human DEFB1/BD-1 Polyclonal Antibody | anti-DEFB1/BD-1 antibody
Anti-DEFB1/BD-1 Antibody
Gene Names
DEFB1; BD1; HBD1; DEFB-1; DEFB101
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
DEFB1/BD-1; Polyclonal Antibody; Anti-DEFB1/BD-1 Antibody; Rabbit Polyclonal (IgG) to Mouse DEFB1/BD-1; DEFB1; BD1; Beta-defensin 1; BD-1; Beta Defensin 1; DEFB-1; DEFB101; Defensin; beta 1; Defensin beta; HBD-1; Beta-defensin-1; HBD1; anti-DEFB1/BD-1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human BD-1
Purity/Purification
Immunoaffinity Purified
Form/Format
Lyophilized from PBS, pH 7.2
Sequence Length
68
Applicable Applications for anti-DEFB1/BD-1 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
IHC-P: 5 ug/ml
WB: 0.1-0.2 ug/ml
IHC-P: 5 ug/ml
WB: 0.1-0.2 ug/ml
Immunogen
E Coli derived recombinant Human BD-1.
Conjugation
Unconjugated
Resuspension Liquid
Sterile water
Preparation and Storage
Store Lyophilized at room temperature up to 1 month.
Reconstituted for up to two weeks at 2-8 degree C.
Aliquot and freeze at -20 degree C for long term storage.
Avoid freeze/thaw cycles.
Reconstituted for up to two weeks at 2-8 degree C.
Aliquot and freeze at -20 degree C for long term storage.
Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Anti-DEFB1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-DEFB1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-DEFB1/BD-1 antibody
Defensins form a family of microbicidal and cytotoxic peptides made byneutrophils. Members of the defensin family are highly similar inprotein sequence. This gene encodes defensin, beta 1, an antimicrobialpeptide implicated in the resistance of epithelial surfaces to microbialcolonization. This gene maps in close proximity to defensin familymember, defensin, alpha 1 and has been implicated in the pathogenesis ofcystic fibrosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
7,420 Da
NCBI Official Full Name
beta-defensin 1 preproprotein
NCBI Official Synonym Full Names
defensin beta 1
NCBI Official Symbol
DEFB1
NCBI Official Synonym Symbols
BD1; HBD1; DEFB-1; DEFB101
NCBI Protein Information
beta-defensin 1
UniProt Protein Name
Beta-defensin 1
UniProt Gene Name
DEFB1
UniProt Synonym Gene Names
BD1; HBD1; BD-1; hBD-1
NCBI Description
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
Uniprot Description
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636).
Research Articles on DEFB1/BD-1
Similar Products
Product Notes
The DEFB1/BD-1 defb1 (Catalog #AAA2400714) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-DEFB1/BD-1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEFB1/BD-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 0.5-2 ug/ml IHC-P: 5 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the DEFB1/BD-1 defb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DEFB1/BD-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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