Rabbit anti-Human DAP Kinase 2 Polyclonal Antibody | anti-DAP antibody

DAP Kinase 2 Antibody

Cat. Num. AAA9404089

• Gene Names: DAPK2; DRP1; DRP-1
• Reactivity: Human
• Applications: Western Blot
• Purity: Antibodies were purified by antigen-affinity chromatography.
• Synonyms: DAP Kinase 2; Polyclonal Antibody; DAP Kinase 2 Antibody; DRP-1 antibody; DRP1 antibody; MGC119312 antibody; DAPK2 antibody; death-associated protein kinase 2 antibody; DAP-kinase-related protein 1 beta isoform antibody; DAP kinase 2 antibody; anti-DAP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total DAP Kinase 2 protein.
• Purity/Purification: Antibodies were purified by antigen-affinity chromatography.
• Form/Format: Rabbit IgG in 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 370

• Applicable Applications for anti-DAP antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500-1:3000
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to a region within amino acids 309 and 370 of DAP kinase 2.
• Target Name: DAP Kinase 2
• Preparation and Storage: Store at -20 degree C

Testing Data

(Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE diluted at 1:1000)

Related Product Information for anti-DAP antibody

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq]

Product Categories/Family for anti-DAP antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 14670383
• NCBI GeneID: 23604
• NCBI Accession #: NP_055141.2
• NCBI GenBank Nucleotide #: NM_014326.3
• UniProt Accession #: Q9UIK4; O75892; Q24JS1; E9JGM7
• Molecular Weight: 55,931 Da
• NCBI Official Full Name: death-associated protein kinase 2
• NCBI Official Synonym Full Names: death-associated protein kinase 2
• NCBI Official Symbol: DAPK2
• NCBI Official Synonym Symbols: DRP1; DRP-1
• NCBI Protein Information: death-associated protein kinase 2
• UniProt Protein Name: Death-associated protein kinase 2
• Protein Family: Death-associated protein
• UniProt Gene Name: DAPK2
• UniProt Synonym Gene Names: DAP kinase 2; DRP-1
• UniProt Entry Name: DAPK2_HUMAN

NCBI Description

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]

Uniprot Description

DAPK2: an ubiquitously expressed protein kinase of the DAPK family. Activated by Ca(2+)/calmodulin. Contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain. Overexpression induces apoptosis. Expressed at high levels in heart, lung and skeletal muscle.

Protein type: Protein kinase, CAMK; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: cytoplasm; cytoplasmic vesicle

Molecular Function: calmodulin binding; protein serine/threonine kinase activity; identical protein binding; protein binding; calmodulin-dependent protein kinase activity; ATP binding

Biological Process: regulation of apoptosis; apoptosis; protein amino acid autophosphorylation; regulation of autophagy; protein amino acid phosphorylation; anoikis