Western Blot (WB)
(CYP26C1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CYP26C1 antibody detected the CYP26C1 protein (arrow).)
Rabbit anti-Human CYP26C1 Polyclonal Antibody | anti-CYP26C1 antibody
CYP26C1 Antibody (C-term)
Western Blot (WB)
(CYP26C1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CYP26C1 antibody detected the CYP26C1 protein (arrow).)
Western Blot (WB)
(CYP26C1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CYP26C1 antibody detected the CYP26C1 protein (arrow).)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with CYP26C1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with CYP26C1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Taimi,M., J. Biol. Chem. 279 (1), 77-85 (2004)
Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008]
Uniprot Description
CYP26C1: Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate). Belongs to the cytochrome P450 family.
Protein type: Cell development/differentiation; Cofactor and Vitamin Metabolism - retinol; EC 1.14.-.-; Oxidoreductase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 10q23.33
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: retinoic acid binding; iron ion binding; retinoic acid 4-hydroxylase activity; heme binding
Biological Process: anterior/posterior pattern formation; negative regulation of retinoic acid receptor signaling pathway; organelle fusion; vitamin metabolic process; central nervous system development; neural crest cell development; xenobiotic metabolic process
Disease: Focal Facial Dermal Dysplasia 4
Research Articles on CYP26C1
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Product Notes
The CYP26C1 cyp26c1 (Catalog #AAA9209450) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 410-439. The CYP26C1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CYP26C1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the CYP26C1 cyp26c1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP26C1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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