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Western Blot (WB) (All lanes: CXXC-type zinc finger protein 1 antibody at 2ug/mlLane 1:THP-1 whole cell lysateLane 2:mouse liver tissueLane 2:mouse spleen tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 76,77 kDaObserved band size: 76 kDa)

Rabbit anti-Human, Mouse CXXC-type zinc finger protein 1 Polyclonal Antibody | anti-CXXC1 antibody

Rabbit anti-human CXXC-type zinc finger protein 1 polyclonal Antibody(CXXC1)

Gene Names
CXXC1; CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
CXXC-type zinc finger protein 1; Polyclonal Antibody; Rabbit anti-human CXXC-type zinc finger protein 1 polyclonal Antibody(CXXC1); CpG-binding protein; PHD finger and CXXC domain-containing protein 1; CXXC1; CFP1; CGBP; PCCX1; PHF18; anti-CXXC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
660
Applicable Applications for anti-CXXC1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human CXXC-type zinc finger protein 1 protein (1-210aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12336 / sc-12339 / sc-25391
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(All lanes: CXXC-type zinc finger protein 1 antibody at 2ug/mlLane 1:THP-1 whole cell lysateLane 2:mouse liver tissueLane 2:mouse spleen tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 76,77 kDaObserved band size: 76 kDa)

Western Blot (WB) (All lanes: CXXC-type zinc finger protein 1 antibody at 2ug/mlLane 1:THP-1 whole cell lysateLane 2:mouse liver tissueLane 2:mouse spleen tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 76,77 kDaObserved band size: 76 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human rectum using MBS1496089 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human rectum using MBS1496089 at dilution 1:100)
Related Product Information for anti-CXXC1 antibody
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,227 Da
NCBI Official Full Name
CXXC-type zinc finger protein 1 isoform 1
NCBI Official Synonym Full Names
CXXC finger protein 1
NCBI Official Symbol
CXXC1
NCBI Official Synonym Symbols
CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
NCBI Protein Information
CXXC-type zinc finger protein 1
UniProt Protein Name
CXXC-type zinc finger protein 1
UniProt Gene Name
CXXC1
UniProt Synonym Gene Names
CFP1; CGBP; PCCX1; PHF18
UniProt Entry Name
CXXC1_HUMAN

NCBI Description

This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 2015]

Uniprot Description

CXXC1: Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 18q12

Cellular Component: cytoplasm; histone methyltransferase complex; nuclear matrix; nuclear speck; nucleoplasm; nucleus

Molecular Function: histone lysine N-methyltransferase activity (H3-K4 specific); protein binding; unmethylated CpG binding; zinc ion binding

Biological Process: cellular protein metabolic process; histone H3-K4 methylation; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription, DNA-dependent; unfolded protein response

Research Articles on CXXC1

Similar Products

Product Notes

The CXXC1 cxxc1 (Catalog #AAA1496089) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human CXXC-type zinc finger protein 1 polyclonal Antibody(CXXC1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CXXC-type zinc finger protein 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-5000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the CXXC1 cxxc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXXC-type zinc finger protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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