Rabbit CX3CL1 Polyclonal Antibody | anti-CX3CL1 antibody
CX3CL1 Antibody BIOTIN
Gene Names
Cx3cl1; CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e
Reactivity
Human, Monkey, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Immobilized antigen affinity chromatography
Synonyms
CX3CL1; Polyclonal Antibody; CX3CL1 Antibody BIOTIN; BIOTIN-Conjugated Fractalkine Antibody; A 152E5.2 antibody; AB030188 antibody; ABCD3 antibody; AI848747 antibody; C-X3-C motif chemokine 1 antibody; C3Xkine antibody; Chemokine C X3 C motif ligand 1 antibody; CX3C membrane anchored chemokine antibody; Cx3cl1 antibody; CXC3 antibody; CXC3C antibody; D8Bwg0439e antibody; FKN antibody; Fractalkine antibody; Neurotactin antibody; NTN antibody; NTT antibody; Processed fractalkine antibody; SCYD 1 antibody; Small inducible cytokine D1 antibody; X3CL1_HUMAN antibody; anti-CX3CL1 antibody
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
395
Applicable Applications for anti-CX3CL1 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
IP: 1:150
WB: 1:500
IP: 1:150
WB: 1:500
Immunogen
Synthetic peptide taken within amino acid reigon 350-395 on mouse Fractalkine protein.
Conjugation
BIOTIN
Molecular Function
CCR chemokine receptor binding; chemokine activity; CX3C chemokine receptor binding; integrin binding
Subcellular Location
Cell Membrane; Single-pass type I membrane protein; Processed fractalkine: Secreted
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for anti-CX3CL1 antibody
Overview: Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1. The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9177350, PubMed:10382755).
Structure: Signal, Transmembrane, Transmembrane helix
Expression: Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis.
Structure: Signal, Transmembrane, Transmembrane helix
Expression: Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,099 Da
NCBI Official Full Name
fractalkine
NCBI Official Synonym Full Names
chemokine (C-X3-C motif) ligand 1
NCBI Official Symbol
Cx3cl1
NCBI Official Synonym Symbols
CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e
NCBI Protein Information
fractalkine
UniProt Protein Name
Fractalkine
Protein Family
UniProt Gene Name
Cx3cl1
UniProt Synonym Gene Names
Cx3c; Fkn; Scyd1
Uniprot Description
Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (). The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9177350, PubMed:10382755).
Research Articles on CX3CL1
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Product Notes
The CX3CL1 cx3cl1 (Catalog #AAA5400376) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CX3CL1 Antibody BIOTIN reacts with Human, Monkey, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CX3CL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 IP: 1:150 WB: 1:500. Researchers should empirically determine the suitability of the CX3CL1 cx3cl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CX3CL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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