Western Blot (WB)
(Anti-CX3CL1 antibody, MBS175123, Western blottingLane 1: Recombinant Mouse Fractalkin Protein 10ngLane 2: Recombinant Mouse Fractalkin Protein 5ngLane 3: Recombinant Mouse Fractalkin Protein 2.5ng )
Rabbit anti-Mouse, Rat CX3CL1 Polyclonal Antibody | anti-CX3CL1 antibody
Anti-CX3CL1 antibody
Western Blot (WB)
(Anti-CX3CL1 antibody, MBS175123, Western blottingLane 1: Recombinant Mouse Fractalkin Protein 10ngLane 2: Recombinant Mouse Fractalkin Protein 5ngLane 3: Recombinant Mouse Fractalkin Protein 2.5ng )
Western Blot (WB)
(Anti-CX3CL1 antibody, MBS175123, Western blottingLane 1: Recombinant Mouse Fractalkin Protein 10ngLane 2: Recombinant Mouse Fractalkin Protein 5ngLane 3: Recombinant Mouse Fractalkin Protein 2.5ng )
Immunohistochemistry (IHC)
(Anti-CX3CL1 antibody, MBS175123, IHC(P)IHC(P): Rat Intestine Tissue )
Immunohistochemistry (IHC)
(Anti-CX3CL1 antibody, MBS175123, IHC(P)IHC(P): Rat Intestine Tissue )
Background: Chemokine(C-X3-C motif) ligand 1, also known as CX3CL1, is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine(in humans) and neurotactin(in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al.(1997) identified a 7-transmembrane high-affinity receptor(CX3CR1; 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.
NCBI and Uniprot Product Information
Uniprot Description
CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: extracellular space; cell surface; cell projection; membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; integral to membrane; extracellular region
Molecular Function: chemokine activity; cytokine activity
Biological Process: platelet activation; positive regulation of transforming growth factor-beta1 production; neutrophil chemotaxis; positive regulation of neuroblast proliferation; positive regulation of cell adhesion; wound healing; positive regulation of smooth muscle cell proliferation; cytokine and chemokine mediated signaling pathway; negative regulation of cytokine secretion; microglial cell activation; chemotaxis; angiogenesis involved in wound healing; leukocyte adhesive activation; macrophage chemotaxis; negative regulation of vasoconstriction; regulation of inhibitory postsynaptic membrane potential; positive regulation of angiogenesis; positive regulation of calcium-independent cell-cell adhesion; immune response; cell adhesion; lymphocyte chemotaxis; positive regulation of cell migration
Research Articles on CX3CL1
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Product Notes
The CX3CL1 cx3cl1 (Catalog #AAA175123) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CX3CL1 antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CX3CL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin. Researchers should empirically determine the suitability of the CX3CL1 cx3cl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CX3CL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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