Rabbit anti-Human CTRB1 Polyclonal Antibody | anti-CTRB1 antibody

CTRB1, ID (CTRB1, CTRB, Chymotrypsinogen B, Chymotrypsin B chain A, Chymotrypsin B chain B, Chymotrypsin B chain C) (Biotin)

Cat. Num. AAA6289871

• Gene Names: CTRB1; CTRB
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CTRB1; Polyclonal Antibody; ID (CTRB1; CTRB; Chymotrypsinogen B; Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C) (Biotin); Chymotrypsin B chain C; anti-CTRB1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-CTRB1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CTRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-171 amino acids from the Central region of human CTRB1.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CTRB1 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CTRB1 antibody detected the CTRB1 protein (arrow).)

Related Product Information for anti-CTRB1 antibody

CTRB1 (Chymotrypsinogen B1) is the inactive precursor of Alpha chymotrypsin, one of a family of serine proteases secreted into the gastrointestinal tract. The zymogen is activated by proteolytic cleavage by trypsin.

Product Categories/Family for anti-CTRB1 antibody

Antibodies; Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 1042161081
• NCBI GeneID: 1504
• NCBI Accession #: NP_001316119.1
• NCBI GenBank Nucleotide #: NM_001329190.1
• UniProt Accession #: P17538
• Molecular Weight: 27,713 Da
• NCBI Official Full Name: chymotrypsinogen B isoform 2
• NCBI Official Synonym Full Names: chymotrypsinogen B1
• NCBI Official Symbol: CTRB1
• NCBI Official Synonym Symbols: CTRB
• NCBI Protein Information: chymotrypsinogen B
• UniProt Protein Name: Chymotrypsinogen B
• Protein Family: Chymotrypsinogen
• UniProt Gene Name: CTRB1

NCBI Description

This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jul 2016]

Uniprot Description

CTRB1: is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011]

Protein type: Apoptosis; EC 3.4.21.1; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q23.1

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: cobalamin metabolic process; extracellular matrix disassembly