Rabbit Creatine kinase B type Polyclonal Antibody | anti-Ckb antibody

Creatine kinase B type Rabbit Polyclonal

Cat. Num. AAA768191

• Gene Names: Ckb; Ckbb; Ckbr
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: Creatine kinase B type; Polyclonal Antibody; Creatine kinase B type Rabbit Polyclonal; anti-Ckb antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 381

• Applicable Applications for anti-Ckb antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Creatine kinase, brain
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS768191 (CKB antibody) at dilution of 1:100)

Testing Data

()

Western Blot (WB)

(human brain tissue were subjected to SDS PAGE followed by western blot with MBS768191 (CKB antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 401461784
• NCBI GeneID: 24264
• NCBI Accession #: NP_036661.3
• NCBI GenBank Nucleotide #: NM_012529.3
• Molecular Weight: 42,725 Da
• NCBI Official Full Name: creatine kinase B-type
• NCBI Official Synonym Full Names: creatine kinase B
• NCBI Official Symbol: Ckb
• NCBI Official Synonym Symbols: Ckbb; Ckbr
• NCBI Protein Information: creatine kinase B-type
• UniProt Protein Name: Creatine kinase B-type
• Protein Family: Creatine kinase
• UniProt Gene Name: Ckb
• UniProt Synonym Gene Names: Ckbb
• UniProt Entry Name: KCRB_RAT

NCBI Description

brain specific isozyme that catalyzed the interconversion of ATP and creatine to ADP and phosphocreatine; may play a role in ATP generation during cerebellar development [RGD, Feb 2006]

Uniprot Description

CKB: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: Amino Acid Metabolism - arginine and proline; EC 2.7.3.2; Kinase, other

Cellular Component: cytoplasm; mitochondrion; myelin sheath; plasma membrane

Molecular Function: ATP binding; creatine kinase activity; protein binding; ubiquitin protein ligase binding

Biological Process: brain development; cellular chloride ion homeostasis; phosphocreatine metabolic process; phosphorylation; substantia nigra development