Creatine Kinase (CK) Assay Kit | Ckb assay kit

Creatine Kinase (CK) Activity Colorimetric Assay Kit

Cat. Num. AAA841514

• Gene Names: Ckb; Ckbb; Ckbr
• Synonyms: Creatine Kinase (CK); Creatine Kinase (CK) Activity Colorimetric Assay Kit; Creatine Phosphokinase (CPK) Activity Colorimetric Assay Kit; Phospho-Creatine Kinase Activity Colorimetric Assay Kit; Ckb assay kit

• Sequence Length: 381

• Preparation and Storage: At -20 degree C; Shelf Life: 12 months

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Ckb assay kit

Background/Introduction: C-Reactive Protein (CRP), named for its capacity to precipitate the somatic C-polysaccharide of Streptococcus pneumoniae, was the first acute-phase protein to be described and is an exquisitely sensitive systemic marker of inflammation and tissue damage. CRP belongs to the pentraxin family of calcium dependent ligand-binding plasma proteins. Human CRP binds with highest affinity to phosphocholine residues, but it also binds to a variety of other autologous and extrinsic ligands, and it aggregates or precipitates the cellular, particulate, or molecular structures bearing these ligands. Autologous ligands include native and modified plasma lipoproteins, damaged cell membranes, a number of different phospholipids and related compounds, small nuclear ribonucleoprotein particles, and apoptotic cells. Extrinsic ligands include many glycan, phospholipid, and other constituents of microorganisms, such as capsular and somatic components of bacteria, fungi, and parasites, as well as plant products. CRP has been associated with cardiovascular disease, atherosclerosis and inflammation, and other human diseases. Human CRP ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of human CRP in plasma, serum or other biological fluid samples. The kit has detection sensitivity limit of 1 ng/mL human CRP. Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples.

Product Categories/Family for Ckb assay kit

Metabolism Assays; Serum Components Metabolism Assays; Metabolism Assays (A-Z)

NCBI and Uniprot Product Information

• NCBI GI #: 401461784
• NCBI GeneID: 24264
• NCBI Accession #: NP_036661.3
• NCBI GenBank Nucleotide #: NM_012529.3
• Molecular Weight: 42,725 Da
• NCBI Official Full Name: creatine kinase B-type
• NCBI Official Synonym Full Names: creatine kinase, brain
• NCBI Official Symbol: Ckb
• NCBI Official Synonym Symbols: Ckbb; Ckbr
• NCBI Protein Information: creatine kinase B-type
• UniProt Protein Name: Creatine kinase B-type
• Protein Family: Creatine kinase
• UniProt Gene Name: Ckb
• UniProt Synonym Gene Names: Ckbb
• UniProt Entry Name: KCRB_RAT

NCBI Description

brain specific isozyme that catalyzed the interconversion of ATP and creatine to ADP and phosphocreatine; may play a role in ATP generation during cerebellar development [RGD, Feb 2006]

Uniprot Description

CKB: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: Amino Acid Metabolism - arginine and proline; Kinase, other; EC 2.7.3.2

Cellular Component: mitochondrion; plasma membrane; myelin sheath

Molecular Function: protein binding; creatine kinase activity; ATP binding

Biological Process: substantia nigra development; phosphocreatine metabolic process; brain development; phosphorylation; cellular chloride ion homeostasis