Goat anti-Human CPT1B Polyclonal Antibody | anti-CPT1B antibody

CPT1B (isoform 1) Carnitine Palmitoyltransferase 1B (muscle)

Cat. Num. AAA628137

• Gene Names: CPT1B; CPTI; CPT1M; MCPT1; CPT1-M; CPTI-M; M-CPT1; MCCPT1
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Affinity Purified; Purified by peptide affinity chromatography.
• Synonyms: CPT1B; Polyclonal Antibody; CPT1B (isoform 1) Carnitine Palmitoyltransferase 1B (muscle); Anti -CPT1B (isoform 1) Carnitine Palmitoyltransferase 1B (muscle); anti-CPT1B antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CPT1B. This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1), isoform c (NP_001138606.1) and isoform d (NP_001138608.1).
• Purity/Purification: Affinity Purified; Purified by peptide affinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.

• Applicable Applications for anti-CPT1B antibody: ELISA (EL/EIA), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA and Immunohistochemistry.; Dilution: Peptide ELISA Titer: 1:16,000; Immunohistochemistry: 3-5ug/ml; In paraffin embedded Human Heart shows staining of myocardial fibres in longitudinal section.
• Immunogen: Synthetic peptide corresponding to C-DIADLFQVPKAYS, from the C Terminus of human CPT1B (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1; NP_001138606.1; NP_001138608.1.)
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(C7906-06B1 (3.8µg/ml) staining of paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)

Related Product Information for anti-CPT1B antibody

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

Product Categories/Family for anti-CPT1B antibody

Antibodies; Abs to Enzymes;  Transferase

NCBI and Uniprot Product Information

• NCBI GI #: 223468678
• NCBI GeneID: 1375
• NCBI Accession #: NP_001138609.1
• NCBI GenBank Nucleotide #: NM_001145137.1
• UniProt Accession #: Q92523; Q13389; Q99655; Q9BY90; B7Z4U4; B7Z5T8; E9PCP2
• Molecular Weight: 87,801 Da
• NCBI Official Full Name: carnitine O-palmitoyltransferase 1, muscle isoform isoform a
• NCBI Official Synonym Full Names: carnitine palmitoyltransferase 1B (muscle)
• NCBI Official Symbol: CPT1B
• NCBI Official Synonym Symbols: CPTI; CPT1M; MCPT1; CPT1-M; CPTI-M; M-CPT1; MCCPT1
• NCBI Protein Information: carnitine O-palmitoyltransferase 1, muscle isoform; carnitine palmitoyltransferase I-like protein; carnitine O-palmitoyltransferase I, mitochondrial muscle isoform
• UniProt Protein Name: Carnitine O-palmitoyltransferase 1, muscle isoform
• Protein Family: Carnitine O-palmitoyltransferase
• UniProt Gene Name: CPT1B
• UniProt Synonym Gene Names: KIAA1670; CPT1-M; CPT I; CPTI-M
• UniProt Entry Name: CPT1B_HUMAN

NCBI Description

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]

Uniprot Description

CPT1B: a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]

Protein type: EC 2.3.1.21; Lipid Metabolism - fatty acid; Transferase; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: mitochondrial outer membrane; mitochondrion; integral to membrane

Molecular Function: carnitine O-palmitoyltransferase activity

Biological Process: fatty acid beta-oxidation; carnitine shuttle; cellular lipid metabolic process