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Western Blot (WB)

Rabbit cox2 Polyclonal Antibody | anti-cox2 antibody

Anti-cox2 Antibody

Gene Names
Ptgs2; COX2; Cox-2; PHS-2; Pghs2; TIS10; PGHS-2
Reactivity
Human, Mouse, Rat. Not yet tested on other species
Applications
ELISA, Western Blot
Purity
Purified
Synonyms
cox2; Polyclonal Antibody; Anti-cox2 Antibody; anti-cox2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat. Not yet tested on other species
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
4150
Applicable Applications for anti-cox2 antibody
ELISA, Western Blot (WB)
Application Notes
Peptide ELISA titer: 1:10,000-1:40,000
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end user
Antibody Type
Primary Antibody
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Synthetic peptide conjugated to KLH
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Western Blot (WB)

Western Blot (WB)
References
(1) Yang,H., Zhang,J., Andreasson,K. and Chen,C. COX-2 oxidative metabolism of endocannabinoids augments hippocampal synaptic plasticity. Mol. Cell. Neurosci. 37 (4), 682-695 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,013 Da
NCBI Official Full Name
Mus musculus prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA
NCBI Official Synonym Full Names
prostaglandin-endoperoxide synthase 2
NCBI Official Symbol
Ptgs2
NCBI Official Synonym Symbols
COX2; Cox-2; PHS-2; Pghs2; TIS10; PGHS-2
NCBI Protein Information
prostaglandin G/H synthase 2; PES-2; PGH synthase 2; PHS II; cyclooxygenase 2; cyclooxygenase-2; glucocorticoid-regulated inflammatory cyclooxygenase; gripghs; macrophage activation-associated marker protein P71/73; prostaglandin H2 synthase 2
UniProt Protein Name
Prostaglandin G/H synthase 2
UniProt Gene Name
Ptgs2
UniProt Entry Name
PGH2_MOUSE

Uniprot Description

COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family.

Protein type: Lipid Metabolism - arachidonic acid; EC 1.14.99.1; Oxidoreductase

Cellular Component: neuron projection; protein complex; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; caveola; nucleus

Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; prostaglandin-endoperoxide synthase activity; peroxidase activity; protein homodimerization activity; enzyme binding; dioxygenase activity; metal ion binding; heme binding; oxidoreductase activity; lipid binding

Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of NF-kappaB import into nucleus; response to lipopolysaccharide; decidualization; sensory perception of pain; prostaglandin biosynthetic process; fatty acid metabolic process; positive regulation of synaptic transmission, glutamatergic; negative regulation of synaptic transmission, dopaminergic; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; regulation of blood pressure; negative regulation of smooth muscle contraction; positive regulation of cell proliferation; angiogenesis; positive regulation of smooth muscle contraction; inflammatory response; fatty acid biosynthetic process; negative regulation of calcium ion transport; cyclooxygenase pathway; positive regulation of synaptic plasticity; learning; memory; prostaglandin metabolic process; regulation of cell proliferation; ovulation; keratinocyte differentiation; response to cytokine stimulus; brown fat cell differentiation; positive regulation of vasoconstriction; positive regulation of fever; lipid metabolic process; response to oxidative stress; anagen; embryo implantation

Research Articles on cox2

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Product Notes

The cox2 ptgs2 (Catalog #AAA416804) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-cox2 Antibody reacts with Human, Mouse, Rat. Not yet tested on other species and may cross-react with other species as described in the data sheet. AAA Biotech's cox2 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot (WB). Peptide ELISA titer: 1:10,000-1:40,000 Western blot analysis: 1:200-500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the cox2 ptgs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "cox2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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