Sequence Information
Prostaglandin Endoperoxide Synthase 2 (PTGS2) Recombinant Protein | PTGS2 recombinant protein
Recombinant Prostaglandin Endoperoxide Synthase 2 (PTGS2)
MGHHHHHHSG SEF-YQVIGGE VYPPTVKDTQ VEMIYPPHIP ENLQFAVGQE VFGLVPGLMM YATIWLREHN RVCDILKQEH PEWGDEQLFQ TSRLILIGET IKIVIEDYVQ HLSGYHFKLK FDPEL
(May be suitable for use in other assays to be determined by the end user.)
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Sequence Information
Sequence Information
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
Uniprot Description
COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family.
Protein type: Oxidoreductase; EC 1.14.99.1; Lipid Metabolism - arachidonic acid
Cellular Component: neuron projection; protein complex; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; caveola; nucleus
Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; prostaglandin-endoperoxide synthase activity; protein homodimerization activity; peroxidase activity; enzyme binding; dioxygenase activity; metal ion binding; heme binding; oxidoreductase activity; lipid binding
Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; response to lipopolysaccharide; positive regulation of NF-kappaB import into nucleus; decidualization; fatty acid metabolic process; prostaglandin biosynthetic process; sensory perception of pain; negative regulation of synaptic transmission, dopaminergic; positive regulation of synaptic transmission, glutamatergic; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; regulation of blood pressure; negative regulation of smooth muscle contraction; positive regulation of cell proliferation; positive regulation of smooth muscle contraction; angiogenesis; inflammatory response; fatty acid biosynthetic process; negative regulation of calcium ion transport; cyclooxygenase pathway; positive regulation of synaptic plasticity; learning; memory; prostaglandin metabolic process; regulation of cell proliferation; ovulation; keratinocyte differentiation; response to cytokine stimulus; positive regulation of vasoconstriction; positive regulation of fever; brown fat cell differentiation; lipid metabolic process; response to oxidative stress; anagen; embryo implantation
Research Articles on PTGS2
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Product Notes
The PTGS2 ptgs2 (Catalog #AAA2010584) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Prostaglandin Endoperoxide Synthase 2 (PTGS2) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) (May be suitable for use in other assays to be determined by the end user.). Researchers should empirically determine the suitability of the PTGS2 ptgs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG SEF-YQVIGG E VYPPTVKDTQ VEMIYPPHIP ENLQFAVGQE VFGLVPGLMM YATIWLREHN RVCDILKQEH PEWGDEQLFQ TSRLILIGET IKIVIEDYVQ HLSGYHFKLK FDPEL. It is sometimes possible for the material contained within the vial of "Prostaglandin Endoperoxide Synthase 2 (PTGS2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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