Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using COX2 Polyclonal Antibody at dilution of 1:500.)
Rabbit anti-Mouse, Rat COX2 Polyclonal Antibody | anti-COX2 antibody
COX2 Polyclonal Antibody
Note: Centrifuge before opening to ensure complete recovery of vial contents.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using COX2 Polyclonal Antibody at dilution of 1:500.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using COX2 Polyclonal Antibody at dilution of 1:500.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Rat nephritis using COX2 Polyclonal Antibody at dilution of 1:500.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Rat nephritis using COX2 Polyclonal Antibody at dilution of 1:500.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Mouse spleen using COX2 Polyclonal Antibody at dilution of 1:500.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded Mouse spleen using COX2 Polyclonal Antibody at dilution of 1:500.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that is a member of the prostaglandin G/H synthase family. The encoded protein converts arachidonic acid to prostaglandin endoperoxide H2 which is a key enzymatic step in prostaglandin biosynthesis. This gene is the inducible prostaglandin G/H synthase family member that is upregulated during inflammation. Aberrant regulation of this gene is associated with cancer progression in several tissues and an increased risk of cardiovascular events. This gene is the target of many non-steroidal anti-inflammatory drugs. [provided by RefSeq, Sep 2015]
Uniprot Description
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Research Articles on COX2
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Product Notes
The COX2 ptgs2 (Catalog #AAA2556054) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COX2 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's COX2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:500-1:1000 Note: Centrifuge before opening to ensure complete recovery of vial contents. Researchers should empirically determine the suitability of the COX2 ptgs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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