Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (CORT antibody (MBS5302834) used at 0.2-1 ug/ml to detect target protein.)

Rabbit CORT Polyclonal Antibody | anti-CORT antibody

CORT antibody

Gene Names
CORT; CST-14; CST-17; CST-29
Applications
Western Blot
Synonyms
CORT; Polyclonal Antibody; CORT antibody; Polyclonal CORT; Anti-CORT; CST-14; CST-29; cortistatin; CST-17; anti-CORT antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
105
Applicable Applications for anti-CORT antibody
Western Blot (WB)
Application Notes
WB: 0.2-1 ug/ml
Biological Significance
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
Cross-Reactivity
Human
Immunogen
CORT antibody was raised in rabbit using the N terminal of CORT as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(CORT antibody (MBS5302834) used at 0.2-1 ug/ml to detect target protein.)

Western Blot (WB) (CORT antibody (MBS5302834) used at 0.2-1 ug/ml to detect target protein.)
Related Product Information for anti-CORT antibody
Affinity purified rabbit polyclonal CORT antibody
Product Categories/Family for anti-CORT antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,532 Da
NCBI Official Full Name
cortistatin preproprotein
NCBI Official Synonym Full Names
cortistatin
NCBI Official Symbol
CORT
NCBI Official Synonym Symbols
CST-14; CST-17; CST-29
NCBI Protein Information
cortistatin
UniProt Protein Name
Cortistatin
Protein Family
UniProt Gene Name
CORT
UniProt Entry Name
CORT_HUMAN

NCBI Description

This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq, Nov 2010]

Uniprot Description

CORT: Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs. Belongs to the somatostatin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular space

Molecular Function: neuropeptide hormone activity; G-protein-coupled receptor binding

Biological Process: synaptic transmission; G-protein signaling, adenylate cyclase inhibiting pathway

Research Articles on CORT

Similar Products

Product Notes

The CORT cort (Catalog #AAA5302834) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CORT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.2-1 ug/ml. Researchers should empirically determine the suitability of the CORT cort for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CORT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.