Western Blot (WB)
(Western Blot (WB) analysis of CLIC3 (F56) pAb at 1:500 dilutionLane1:3T3-L1 whole cell lysate (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:HCC827 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:H1792 whole cell lysate (40ug))
Rabbit CLIC3 Polyclonal Antibody | anti-CLIC3 antibody
CLIC3 (F56) Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CLIC3; Polyclonal Antibody; CLIC3 (F56) Polyclonal Antibody; Chloride intracellular channel protein 3; anti-CLIC3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CLIC3 (F56) polyclonal antibody detects endogenous levels of CLIC3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
236
Applicable Applications for anti-CLIC3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 31-80 of Human CLIC3.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of CLIC3 (F56) pAb at 1:500 dilutionLane1:3T3-L1 whole cell lysate (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:HCC827 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:H1792 whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of CLIC3 (F56) pAb at 1:500 dilutionLane1:3T3-L1 whole cell lysate (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:HCC827 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:H1792 whole cell lysate (40ug))
Related Product Information for anti-CLIC3 antibody
CLIC3 (chloride intracellular channel protein 3) is a member of the highly conserved family of chloride ion channels (CLICs) that function in both soluble and integral membrane forms. Chloride channels regulate cellular traffic of chloride ions, a critical component of all living cells. They are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLIC3 is found in a variety of tissues but is highly expressed in placenta, brain and heart. CLIC3 predominantly localizes to the nucleus and stimulates chloride ion channel activity when expressed in cells. In addition, CLIC3 interacts with ERK 7 and may play a role in the regulation of cell proliferation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 27kDa
NCBI Official Full Name
chloride intracellular channel protein 3
UniProt Protein Name
Chloride intracellular channel protein 3
Protein Family
UniProt Gene Name
CLIC3
UniProt Entry Name
CLIC3_HUMAN
Uniprot Description
CLIC3: Can insert into membranes and form chloride ion channels. May participate in cellular growth control. Belongs to the chloride channel CLIC family.
Protein type: Membrane protein, integral; Channel, chloride
Chromosomal Location of Human Ortholog: 9q34.3
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; chloride channel activity; voltage-gated ion channel activity
Biological Process: chloride transport; signal transduction
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Product Notes
The CLIC3 clic3 (Catalog #AAA3004342) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLIC3 (F56) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLIC3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CLIC3 clic3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLIC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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