Western Blot (WB)
(CLEC14A polyclonal antibody. Western Blot analysis of CLEC14A expression in human liver.)
Mouse anti-Human CLEC14A Polyclonal Antibody | anti-CLEC14A antibody
CLEC14A (C-type Lectin Domain Family 14 Member A, Epidermal Growth Factor Receptor 5, EGFR-5, C14orf27, EGFR5, UNQ236/PRO269)
Gene Names
CLEC14A; CEG1; EGFR-5; C14orf27
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
CLEC14A; Polyclonal Antibody; CLEC14A (C-type Lectin Domain Family 14 Member A; Epidermal Growth Factor Receptor 5; EGFR-5; C14orf27; EGFR5; UNQ236/PRO269); Anti -CLEC14A (C-type Lectin Domain Family 14 Member A; anti-CLEC14A antibody
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CLEC14A.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MRPAFALCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGALSTVRAGAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDPGGLESDTLQWVEEPQRSCTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCPAPRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGVPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSIPEIPRWGSQSTMSTLQMSLQAESKATITPSGSVISKFNSTTSSATPQAFDSSSAVVFIFVSTAVVVLVILTMTVLGLVKLCFHESPSSQPRKESMGPPGLESDPEPAALGSSSAHCTNNGVKVGDCDLRDRAEGALLAESPLGSSDA
Applicable Applications for anti-CLEC14A antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human CLEC14A, aa1-490 (NP_778230.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(CLEC14A polyclonal antibody. Western Blot analysis of CLEC14A expression in human liver.)
Western Blot (WB)
(CLEC14A polyclonal antibody. Western Blot analysis of CLEC14A expression in human liver.)
Western Blot (WB)
(CLEC14A polyclonal antibody. Western Blot analysis of CLEC14A expression in HepG2.)
Western Blot (WB)
(CLEC14A polyclonal antibody. Western Blot analysis of CLEC14A expression in HepG2.)
Western Blot (WB)
(Western Blot analysis of CLEC14A expression in transfected 293T cell line by CLEC14A polyclonal antibody. Lane 1: CLEC14A transfected lysate (53.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CLEC14A expression in transfected 293T cell line by CLEC14A polyclonal antibody. Lane 1: CLEC14A transfected lysate (53.9kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-CLEC14A antibody
CLEC14A (C-type lectin domain family 14 member A; also EGFR5) is a 51kD (predicted) member of the C-type lectin domain family of proteins. It is a type I transmembrane protein, apparently expressed in brain and about which little is known. Mature human CLEC14A is 469aa in length. It contains a 376aa extracellular region (aa22-397) and a 72aa cytoplasmic domain. The extracellular region shows one C-type lectin like domain (aa32-175) and an EGF-like region (aa245-287). Over aa2-397, human CLEC14A shares 66% and 81ª identity with mouse and canine CLEC14A, respectively.
Product Categories/Family for anti-CLEC14A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,636 Da
NCBI Official Full Name
C-type lectin domain family 14 member A
NCBI Official Synonym Full Names
C-type lectin domain family 14, member A
NCBI Official Symbol
CLEC14A
NCBI Official Synonym Symbols
CEG1; EGFR-5; C14orf27
NCBI Protein Information
C-type lectin domain family 14 member A; epidermal growth factor receptor 5; ClECT and EGF-like domain containing protein
UniProt Protein Name
C-type lectin domain family 14 member A
Protein Family
UniProt Gene Name
CLEC14A
UniProt Synonym Gene Names
C14orf27; EGFR5; EGFR-5
UniProt Entry Name
CLC14_HUMAN
NCBI Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]
Uniprot Description
CLEC14A:
Protein type: Membrane protein, integral; Protease
Chromosomal Location of Human Ortholog: 14q21.1
Cellular Component: integral to membrane
Molecular Function: carbohydrate binding
Research Articles on CLEC14A
Similar Products
Product Notes
The CLEC14A clec14a (Catalog #AAA641848) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CLEC14A (C-type Lectin Domain Family 14 Member A, Epidermal Growth Factor Receptor 5, EGFR-5, C14orf27, EGFR5, UNQ236/PRO269) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC14A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the CLEC14A clec14a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRPAFALCLL WQALWPGPGG GEHPTADRAG CSASGACYSL HHATMKRQAA EEACILRGGA LSTVRAGAEL RAVLALLRAG PGPGGGSKDL LFWVALERRR SHCTLENEPL RGFSWLSSDP GGLESDTLQW VEEPQRSCTA RRCAVLQATG GVEPAGWKEM RCHLRANGYL CKYQFEVLCP APRPGAASNL SYRAPFQLHS AALDFSPPGT EVSALCRGQL PISVTCIADE IGARWDKLSG DVLCPCPGRY LRAGKCAELP NCLDDLGGFA CECATGFELG KDGRSCVTSG EGQPTLGGTG VPTRRPPATA TSPVPQRTWP IRVDEKLGET PLVPEQDNSV TSIPEIPRWG SQSTMSTLQM SLQAESKATI TPSGSVISKF NSTTSSATPQ AFDSSSAVVF IFVSTAVVVL VILTMTVLGL VKLCFHESPS SQPRKESMGP PGLESDPEPA ALGSSSAHCT NNGVKVGDCD LRDRAEGALL AESPLGSSDA. It is sometimes possible for the material contained within the vial of "CLEC14A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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