Western Blot (WB)
(CL052 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CL052 antibody detected the CL052 protein (arrow).)
Rabbit anti-Human CL052 Polyclonal Antibody | anti-RITA1 antibody
CL052 Antibody (N-term)
Western Blot (WB)
(CL052 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CL052 antibody detected the CL052 protein (arrow).)
Western Blot (WB)
(CL052 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CL052 antibody detected the CL052 protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
RITA1: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. Belongs to the RITA family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear export
Chromosomal Location of Human Ortholog: 12q24.13
Cellular Component: nucleoplasm; Golgi apparatus; centrosome; cytoplasm; nucleus
Molecular Function: tubulin binding; protein binding
Biological Process: Notch signaling pathway; neurogenesis; nuclear export; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter
Research Articles on RITA1
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Product Notes
The RITA1 rita1 (Catalog #AAA9201845) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 44-72. The CL052 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CL052 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RITA1 rita1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CL052, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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